Results 51 to 60 of about 43,835 (227)

Biological Reinforced Concrete for Cartilage Repair With 3D Printing

Advanced Science, EarlyView.
Inspired by concrete rebar structures in engineering, the concept of biological reinforced concrete uses 3D‐printed ultrafine fiber networks (UFNs) as biodegradable “biorebars”， hybrid biohydrogels as “biocement”， and stem cells as “bioactive aggregates” to fabricate biomimetic cartilage.
Yuewei Chen, Tao Fu, Zhongfei Zou, Yanming Liu, Jianguo Zhu, Binhong Teng, Ke Yao, Haibin Li, Jiachun Li, Zhijian Xie, Yong He   +10 more
wiley   +1 more source

Prognóstico pulmonar em prematuros Pulmonary prognosis in preterm infants

Jornal de Pediatria, 2005
OBJETIVO: O aumento da sobrevida de prematuros traz o desafio de lidar com um amplo espectro de doenças pulmonares crônicas, incluindo displasia broncopulmonar, síndrome de Wilson-Mikity e sibilância recorrente. Este artigo discute o prognóstico pulmonar
Luciana Friedrich, Andréa L. Corso, Marcus H. Jones   +2 more
doaj   +1 more source

PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]

, 2019
Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin, Silva, Eduardo A, Stilhano, Roberta S, Yamaguchi, Fabio SM   +3 more
core   +1 more source

Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation

Advanced Science, EarlyView.
Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing, Shuang Liang, Wei Cao, Qulian Guo, Wangyuan Zou   +4 more
wiley   +1 more source

Engineering Extracellular Vesicles Derived from 3D Cultivation of BMSCs Enriched with HGF Ameliorate Sepsis‐Induced Lung Epithelial Barrier Damage

Advanced Science, EarlyView.
3D culture of MSCs upregulates gene expression of matrix metalloproteinases (MMPs), growth factors (GFs), and increases the production of extracellular vesicles (EVs). Proteomic analysis reveals 642 upregulated proteins in 3D‐EVs, including HGF. These 3D‐EVs, enriched with HGF, protect lung epithelial cells from apoptosis and barrier damage in septic ...
Yong Chen, Feihong Lin, Tong Zhang, Zhuoran Xiao, Yuanli Chen, Dongsheng Hua, Yu Wang, Juan Wei, Tian Jin, Xin Lv   +9 more
wiley   +1 more source

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang, Kexin He, Ruixue Huo, Weihan Li, Shan Zhang, Lu‐Ju Jiang, Hao Wu, Minhao Yu, Shu‐Heng Jiang, Junli Xue   +9 more
wiley   +1 more source

Mary Ellen Avery’s Research Career- Remembrance of Things Past

Frontiers in Pediatrics, 2014
Mary Ellen Avery’s research is recognized as a milestone in biomedical research. She had discovered the underlying cause of Hyaline Membrane Disease, surfactant deficiency, fostering ever more vigorous efforts to reduce neonatal mortality in the ...
John Steven Torday
doaj   +1 more source

Origins of neonatal intensive care in the UK [PDF]

, 2001
Chaired by Professor Robert Boyd, this seminar reviewed the development and changes in care of the newborn in the UK over the past 50 years. Advances in techniques were described, such as mechanical ventilation, total parenteral nutrition and continuous ...

core  

Vestibular Drop Attacks and Meniere's Disease as Results of Otolithic Membrane Damage -- A Numerical Model [PDF]

arXiv, 2021
BACKGROUND: Meniere's Disease (MD) is a condition of the inner ear with symptoms affecting both vestibular and hearing functions. Some patients with MD experience vestibular drop attacks (VDAs), which are violent falls caused by spurious vestibular signals from the utricle and/or saccule. Recent surgical work has shown that patients who experience VDAs
arxiv  

Morphology of the sternoclavicular joint and its microanatomical changes in response to osteoarthritic degeneration

Clinical Anatomy, EarlyView.
Abstract Although the sternoclavicular joint shares structural similarities with the knee and hip joints as a diarthrodial joint, its biomechanics differ significantly due to its non‐weight‐bearing nature. Nevertheless, it is subject to considerable loading, leading to increased susceptibility to osteoarthritis, a prevalent condition characterized by ...
Sophie Mok, Yousef Almajed, Abdulaziz Alomiery, Roger Soames, Abduelmenem Alashkham   +4 more
wiley   +1 more source