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Aggrecan immobilizes to perineuronal nets through hyaluronan-dependent and hyaluronan-independent binding activities. [PDF]

open access: yesJ Biol Chem
Otsuka MY   +7 more
europepmc   +1 more source

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super-Resolution Imaging and Genome Modification. [PDF]

open access: yesAdv Sci (Weinh)
Ge X   +16 more
europepmc   +1 more source
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Hyaluronan and morphogenesis

Birth Defects Research Part C: Embryo Today: Reviews, 2004
AbstractIn the past decade, there has been an explosion of interest in hyaluronan, an often misunderstood, biochemically simple, yet functionally complex carbohydrate polymer that is a resident of many extracellular matrices. Previously thought of as a passive, space‐filling component of the extracellular matrix, the so‐called “goo” concept, hyaluronan
Andrew P. Spicer, Janet Y.L. Tien
openaire   +3 more sources

Role of hyaluronan and hyaluronan synthase in endometrial cancer

Oncology Reports, 2005
The aim of this study was to determine if the immunohistochemical expression of hyaluronan synthase (HAS) and serum levels of hyaluronan correlate with the clinicopathological manifestations of endometrial carcinoma. Sera were obtained from 59 endometrial cancer patients and 22 post-menopausal healthy women.
Tameko Kishida   +7 more
openaire   +3 more sources

Regulation of hyaluronan synthesis and the interaction of hyaluronan with cells [PDF]

open access: possibleActa Orthopaedica Scandinavica, 1995
Hyaluronan is a high molecular weight polysaccharide ubiquitously found in the extracellular matrix. It acts as a lubricant in joints and tissues and provides stability and elasticity to the extracellular matrix. In addition, hyaluronan is directly or indirectly implicated in cell growth, angiogenesis, differentiation and malignant tumor invasion (for ...
Paraskevi Heldin   +6 more
openaire   +1 more source

Hyaluronan–Phospholipid Interactions

Journal of Structural Biology, 1997
Hyaluronan-phospholipid interactions have been studied in vitro by negative staining and rotary shadowing electron microscopy. Hyaluronan (HA) molecules of different molecular weights (around 170,000; 740,000, and 1.9 x 10(6) Da) were added to phospholipid suspensions (DPPC or egg lecithin) that were in the form of either unilamellar particles or ...
RONCHETTI, Ivonne   +4 more
openaire   +4 more sources

Hyaluronan

Cellular and Molecular Life Sciences, 2007
The polysaccharide hyaluronan is an essential component of the vertebrate extracellular matrix and also produced by viruses, bacteria and fungi. Although the hyaluronan polymer is simply a disaccharide that repeats many thousands of times, it has an amazing array of biological functions and medical uses.
openaire   +3 more sources

Hyaluronan in morphogenesis

Journal of Internal Medicine, 1997
Toole BP (Tufts University School of Medicine, Boston, MA, USA). Hyaluronan in morphogenesis (Minisymposium: Hyaluronan). J Intern Med 1997; 242: 35–40.Pericellular matrices surrounding migrating and proliferating cells in the developing embryo, in regenerating tissues and in other dynamic cellular events, such as tumour cell invasion, are enriched in ...
openaire   +4 more sources

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