Results 1 to 10 of about 181,818 (312)

The Effect of Hyaluronic Acid on MMP-9 Expression in Trabecular Meshwork Cell Culture of Patient with Primary Open Angle Glaucoma

open access: diamondJournal of Agromedicine and Medical Sciences (AMS), 2017
In primary open angle glaucoma, decrease of hyaluronic acid level is related to extracellular matrix deposition of trabecular meshwork. Extracellular matrix deposition will increase humor aqueous outflow resistance which in turn increase the intraocular ...
Cicih Komariah   +2 more
doaj   +3 more sources

The classification and therapeutic applications of molecular motors

open access: yesEuropean Journal of Medicinal Chemistry Reports, 2021
The molecular motors are protein molecules which can be teamed up to form the active mobile nanomachine with special functions. As a new type of therapeutic target different from normal enzymes or receptors, molecular motor plays a unique role in the ...
Mingyuan Li   +10 more
doaj   +1 more source

Prospective bacterial and fungal sources of hyaluronic acid: A review

open access: yesComputational and Structural Biotechnology Journal, 2022
The unique biological and rheological properties make hyaluronic acid a sought-after material for medicine and cosmetology. Due to very high purity requirements for hyaluronic acid in medical applications, the profitability of streptococcal fermentation ...
E.V. Shikina   +3 more
doaj   +1 more source

“Nanomaterials of curcumin-hyaluronic acid”: their various methods of formulations, clinical and therapeutic applications, present gap, and future directions

open access: yesFuture Journal of Pharmaceutical Sciences, 2021
Background Nanomaterials of curcumin with hyaluronic acid have gained a lot of attention for potential therapeutic applications of curcumin and hyaluronic acid with or without other additional drugs.
Tanzeel Rehman Charan   +6 more
doaj   +1 more source

The Impact of Hyaluronic Acid on Tendon Physiology and Its Clinical Application in Tendinopathies

open access: yesCells, 2021
The physical–chemical, structural, hydrodynamic, and biological properties of hyaluronic acid within tendons are still poorly investigated. Medical history and clinical applications of hyaluronic acid for tendinopathies are still debated. In general, the
Francesco Oliva   +5 more
doaj   +1 more source

Characterization of a Hyaluronic Acid Utilization Locus and Identification of Two Hyaluronate Lyases in a Marine Bacterium Vibrio alginolyticus LWW-9

open access: yesFrontiers in Microbiology, 2021
Hyaluronic acid (HA) is a negatively charged and linear polysaccharide existing in the tissues and body fluids of all vertebrates. Some pathogenic bacteria target hyaluronic acid for adhesion and/or infection to host cells.
Xiaoyi Wang   +11 more
doaj   +1 more source

Retinoic acid induces hyaluronic acid production through the klotho-mediated EGFR signaling pathway in human epidermal keratinocytes [PDF]

open access: yesArchives of Biological Sciences, 2022
All-trans retinoic acid (RA) is an effective anti-aging chemical substance widely used in skin-care products. RA compromises epidermal differentiation and induces keratinocyte proliferation, causing hyaluronic acid production through mechanisms that are ...
Choi Hyangtae   +4 more
doaj   +1 more source

F7 and topotecan co-loaded thermosensitive liposome as a nano-drug delivery system for tumor hyperthermia

open access: yesDrug Delivery, 2020
In order to enhance the targeting efficiency and reduce anti-tumor drug’s side effects, topotecan (TPT) and F7 were co-loaded in thermosensitive liposomes (F7-TPT-TSL), which show enhanced permeability and retention in tumors, as well as local controlled
Chunyang Du   +8 more
doaj   +1 more source

Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle

open access: yesNature Communications, 2023
Hyaluronic acid is a major component of extracellular matrix which plays an important role in development, cellular response to injury and inflammation, cell migration, and cancer.
Yang Zhao   +13 more
doaj   +1 more source

Combining hyaluronic acid with chitosan enhances gene delivery [PDF]

open access: yes, 2014
The low gene transfer efficiency of chitosan-DNA polyplexes is a consequence of their high stability and consequent slow DNA release. The incorporation of an anionic polymer is believed to loosen chitosan interactions with DNA and thus promote higher ...
Bitoque, Diogo   +2 more
core   +3 more sources

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