Results 121 to 130 of about 2,775,700 (254)

Discrete 2D Material Programming for 3D Shaping and Morphogenesis‐Inspired 4D Bioprinting

Advanced Science, EarlyView.
Cell‐compatible discrete 2D material programming enables 2‐to‐3D shape transformation and morphogenesis‐inspired 4D bioprinting. By patterning cell‐supportive microdomains within a responsive hydrogel, the approach programs in‐plane growth to encode target metrics.
Fereshteh Family, Aneela Davuluri, Athulya Martin, Kyungsuk Yum   +3 more
wiley   +1 more source

Photoimmobilization of sulphated hyaluronic acid for antithrombogenicity

, 1997
Anticoagulant polymer sulfated hyaluronic acid was patterned immobilized on a poly(ethylene terephthalate) (PET) film in a specific pattern by photolithography. Hyaluronic acid was sulfated by a sulfur trioxide-pyridine complex.
Lamponi, Stefania, Barbucci, Rolando, Magnani, Agnese, Chen, Guoping, Imanishi, Yukio, Ito, Yoshihiro, Stefania Lamponi, Yoshihiro Ito, Yukio Imanishi, Guoping Chen, Rolando Barbucci, Agnese Magnani   +11 more
core   +1 more source

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Advanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou, Xiaoxue Zhu, Runhan Zhu, Chengchu Xue, Qinyu Zhang, Mengke Li, Ting Yu, Yuzhen Gao, Zhi Ruan, Ying Fu, Yunlei Xianyu, Jun Zhang   +11 more
wiley   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Comparing the results of knee osteoarthritis treatment with intra-articular injection of steroid (methylprednisolone) and hyaluronic acid [PDF]

Caspian Journal of Internal Medicine
Background: Treatments for osteoarthritis, including steroids and nonsteroidal anti-inflammatory drugs, are not very satisfactory. Therefore, we decided to compare the therapeutic results of intra-articular injection of hyaluronic acid and ...
Seyyed Reza Aghapour, Hamid Mohammadi, Seyyed Poyan Aghapour, Khashayar Farnoud, Yasin Sharifzadeh   +4 more
doaj  

PROCESS FOR OBTAINING HYALURONIC ACID OF DEFINED MOLECULAR WEIGHT

, 2012
PROCESS FOR OBTAINING HYALURONIC ACID OF DEFINED MOLECULAR WEIGHT ABSTRACT A process is described for obtaining, in an innovative, simple and economical manner, hyaluronic acid and hyaluronans at varying molecular weight.
D'AGOSTINO, Antonella, DE ROSA, Alfredo, LA GATTA, Annalisa, SCHIRALDI, Chiara   +3 more
core  

Hyaluronic acid hydrogel materials [PDF]

, 2008
textHyaluronic acid (HA) is one of the primary chemical building blocks of the extracellular matrix and thus is an attractive material for biomedical applications.
Zawko, Scott Andrew
core  

THE HISTOCHEMISTRY OF HYALURONIC ACID-CONTAINING MUCOSUBSTANCES

, 1973
Digestion of histologic sections with Streptomyces hyaluronidase releases hyaluronic acid from hyaluronic acid-containing mucosubstances. Such treatment diminishes noticeably or eliminates the alcianophilia (pH 2.5) and metachromatic azurophilia (pH 4.5)
KAZUYORI YAMADA, KENICHI HIRANO
core   +1 more source

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

Advanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian, Shen Zhang, Bolin Wu, Yichi Chen, Haitao Shang, Haoyan Tan, Chunyue Wang, Weichen Xu, Huixiong Xu, Haohao Yin, Wen Cheng   +10 more
wiley   +1 more source