Results 131 to 140 of about 108,598 (297)
NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks
Advanced Science, EarlyView.This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang +10 more
wiley +1 more source
Nada J Alghamdi,1,* Serene R Almuhaidib,2,* Abdulmajeed S Alharbi,2,* Abdullah Ali N Aljalfan,1,* Khalid M Al-Husain1 1Department of Dermatology, King Fahd University Hospital, Al Khobar, Saudi Arabia; 2College of Medicine, Imam ...
Alghamdi NJ +4 more
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Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Advanced Science, EarlyView.Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley +1 more source
Hyaluronic acid as a pulpotomy material in primary molars: an up to 30 months retrospective study
BMC Oral HealthBackground The aim of this retrospective study was to determine the long-term clinical and radiographic success of our previous randomized clinical trial and to compare the success of hyaluronic acid, with the widely used formocresol and ferric sulphate ...
Batın Ilgıt Sezgin +3 more
doaj +1 more source
Cross-linked hyaluronic acid gel occlusive device for the treatment of dry eye syndrome
, 2018 John P Fezza Center for Sight, Sarasota, FL, USA Purpose: A new cross-linked hyaluronic acid (xlHA) gel occlusive device was assessed for safety and efficacy in the treatment of dry eyes.Methods: This was an institutional review board-approved, single ...
Fezza JP
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Tissue injury, including extracellular matrix (ECM) degradation, is a hallmark of group A Streptococcus (GAS) skin infection and is partially mediated by M proteins which possess lectin-like properties.
Proctor, Emma-Jayne +10 more
core +1 more source
Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis
Advanced Science, EarlyView.This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou +23 more
wiley +1 more source
Anti-Inflammatory Effects of the 35kDa Hyaluronic Acid Fragment (B-HA/HA35)
, 2023 XiaoXiao Jia,1,2,* Ming Shi,3,* Qifei Wang,1,2 Jessica Hui,4 Joshua Hui Shofaro,1,2 Ryenchindorj Erkhembayar,5 Mizhou Hui,1,2 Chenzhe Gao,1 Munkh-Amgalan Gantumur1 1College of Life Science, Northeast Agricultural University, Harbin, People’s ...
Gantumur MA +8 more
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