Results 131 to 140 of about 109,214 (299)
Advanced Science, EarlyView.A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo +5 more
wiley +1 more source
Reduction-sensitive CD44 receptor-targeted hyaluronic acid derivative micelles for doxorubicin delivery [PDF]
, 2018 Yishun Yang,1 Yuan Zhao,2 Jinshuai Lan,1 Yanan Kang,3 Tong Zhang,1 Yue Ding,1 Xinyu Zhang,1 Lu Lu3 1Experiment Centre of Teaching and Learning, Shanghai University of Traditional Chinese Medicine, Shanghai, China; 2Experiment Centre for Science and ...
Kang YN +7 more
core
Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment
Advanced Science, EarlyView.Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen +15 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan +5 more
wiley +1 more source
Preparation of hyaluronic acid-based nanofibers via electrospinning [PDF]
, 2016 Tato práce se zabývá nalezením optimálních podmínek pro zvláknění kyseliny hyaluronové (HA) metodou elektrostatického zvlákňování z volné hladiny. Kyselina hyaluronová je přírodní polysacharid s širokým využitím v oblasti tkáňového inženýrství. Vytvoření
Klíčová, Markéta
core +1 more source
Advanced Science, EarlyView.Schematic illustration of a tumor microenvironment‐responsive nanoreactor for imaging‐guided induction of disulfidptosis in pancreatic cancer via metabolic interference and redox catalysis. (A) Stepwise fabrication of Pht@HMnO2‐HA, including MnO2 growth on a SiO2 template, template removal to form hollow mesoporous MnO2, Pht loading, and subsequent ...
Rui Fu +10 more
wiley +1 more source
Using hyaluronic acid-functionalized pH stimuli-responsive mesoporous silica nanoparticles for targeted delivery to CD44-overexpressing cancer cells [PDF]
, 2016 Zhihui Wang,* Yongfeng Tian,* Hua Zhang, Yanmei Qin, Dong Li, Li Gan, Fanhong Wu Department of Pharmaceutical Engineering, School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, People’s Republic of ...
Li D +6 more
core
Advanced Science, EarlyView.Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou +16 more
wiley +1 more source
Comparing the results of knee osteoarthritis treatment with intra-articular injection of steroid (methylprednisolone) and hyaluronic acid [PDF]
Caspian Journal of Internal MedicineBackground: Treatments for osteoarthritis, including steroids and nonsteroidal anti-inflammatory drugs, are not very satisfactory. Therefore, we decided to compare the therapeutic results of intra-articular injection of hyaluronic acid and ...
Seyyed Reza Aghapour +4 more
doaj