Results 301 to 310 of about 175,708 (360)

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

open access: yesAdvanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong   +6 more
wiley   +1 more source

Innate and Adaptive Immune Responses to Clinical Hyaluronic Acid Fillers. [PDF]

open access: yesJ Cosmet Dermatol
Hooks JST   +8 more
europepmc   +1 more source

Prolonged Cell Encapsulation and Gravity‐independent Filamented Light Biofabrication of Muscle Constructs

open access: yesAdvanced Science, EarlyView.
A gravity‐independent filamented light (G‐FLight) projection method is presented for rapid biofabrication of anisotropic tissues, demonstrated with muscle constructs as a target application. Specialized photocrosslinkable resins enable refrigeration or cryopreservation with encapsulated cells.
Michael Winkelbauer   +13 more
wiley   +1 more source

Targeting Fibrotic Scarring by Mechanoregulation of Il11ra1+/Itga11+ Fibroblast Patterning Promotes Axon Growth after Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
This study demonstrates that a hydrogel with mechanical properties matching the spinal cord directs fibroblast alignment, reshaping fibrotic scars into parallel matrices. A specific fibroblast subset mediates extracellular matrix remodeling through mechanotransduction, promoting axonal regeneration and neural reconnections, revealing potential ...
Longyou Xiao   +11 more
wiley   +1 more source

Hyaluronidases improve the hyaluronic acid yield during the fermentation of <i>Streptococcus zooepidemicus</i>. [PDF]

open access: yesFront Bioeng Biotechnol
Kang CL   +13 more
europepmc   +1 more source

MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang   +18 more
wiley   +1 more source

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