Results 71 to 80 of about 77,142 (304)

Efficacy of betamethasone, hyaluronidase and its combination on mouth opening, burning sensation and QOL in patients with OSF

Journal of Oral Biology and Craniofacial Research, 2020
Objectives: To assess the efficacy of betamethasone, hyaluronidase and its combination on mouth opening, burning sensation and quality of life (QOL) in patients with oral submucous fibrosis.
Mohd Saalim, Kaustubh Sansare, Ibrahim K. Ali, Heena Sonawane, Neha Singla, Kavita Vanga, Ruchika Kapoor, Freny R. Karjodkar   +7 more
doaj   +1 more source

Role of hyaluronidase as an adjuvant in local anesthesia for cataract surgery

Indian Journal of Ophthalmology, 2023
Cataract surgery ranks among the commonest procedures performed worldwide. Approximately 51% of blindness worldwide is related to cataracts, affecting about 65.2 million people worldwide and more so in developing countries. Over the years, there has been
Arthi Mohankumar, Mohan Rajan
doaj   +1 more source

Impact of bidirectional relationships between streptococcus anginosus group and host tissue matrix components on cellular activity: Role in establishment of infection [PDF]

, 2003
This paper investigates pathogenic mechanisms of the Streptococcus anginosus group (SAG) of bacteria which influence the biological activity of periodontal ligament (PDL) cells, endothelial cells and also how matrix proteins produced by these host cells ...
Waddington, Rachel J., Landrygan-Bakri, Janine, Wilson, Melanie, Williams, David W., Lewis, Michael Alexander Oxenham   +4 more
core   +10 more sources

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Suppression of hyaluronidase reduces invasion and establishment of Haemonchus contortus larvae in sheep

Veterinary Research, 2020
Haemonchus contortus is a hematophagous endoparasite of small ruminants, which is responsible for huge economic losses in livestock sector. Hyaluronidase produced by infective larvae of H.
Xiangshu Yang, Sawar Khan, Xiaochao Zhao, Jiayan Zhang, Ayesha Nisar, Xingang Feng   +5 more
doaj   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

Effects of Payena dasyphylla (Miq.) on hyaluronidase enzyme activity and metalloproteinases protein expressions in interleukin-1beta stimulated human chondrocytes cells [PDF]

, 2013
Background: Hyaluronidases have been found as the target enzymes in the development of osteoarthritis (OA) disease. While there is still no curative treatment for this disease, recent studies on the treatment of OA were focused on the effectiveness of ...
AAA Azlim, AJ Fosang, AM Valdes, BV Shlopov, C Kandaswami, CAB Clemetson, CR Flannery, DD Dean, E Hedbom, EJ Menzel, F Finger, FE Silverstein, G Chow, G Chow, G Kreil, G Murphy, H Nagase, J Torel, J Zhishen, JL Reissig, JW McClure, K Meyer, Kamini Citalingam, Khozirah Shaari, L Long, M Tagashira, MB Goldring, MB Pérez, MD Tortorella, MM Cowan, MW Guntenhoner, NI Hutchinson, P Borden, P Reboul, PG Mitchell, Q Nguyen, R Stern, RC Billinghurst, RE Hughes, S Chubinskaya, Seema Zareen, SK Benerjee, Syahida Ahmad, T Nakamura, V Knauper, VL Singleton, X Han, Y Lu, YE Henrotin   +48 more
core   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Lutein derived from Xenostegia tridentata exhibits anticancer activities against A549 lung cancer cells via hyaluronidase inhibition.

PLoS ONE
Hyaluronidase has been emerging as a potential target for cancer treatment. Herein, the anticancer effects against A549 NSCLC cells and hyaluronidase inhibitory activity of the ethanol extract of Xenostegia tridentata (L.) D.F.
Jaruwan Chatwichien, Natthawat Semakul, Saranphong Yimklan, Nutchapong Suwanwong, Prakansi Naksing, Somsak Ruchirawat   +5 more
doaj   +1 more source

Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections [PDF]

, 2019
Bacterial invasion of synovial joints, as in infectious or septic arthritis, can be difficult to treat in both veterinary and human clinical practice.
Conlon, Brian P., Gilbertie, Jessica M., Hickok, Noreen J., Jacob, Megan E., Parvizi, Javad, Schaer, Thomas P., Schnabel, Lauren V., Shapiro, Irving   +7 more
core   +2 more sources