Late hyaluronidase injection in local anesthesia: Morphofunctional evaluation in rat sciatic nerve block [PDF]
Introduction: Despite the enhancing effects of hyaluronidase (HYAL) over duration of anesthesia, this enzyme could cause adverse effects when injected concomitantly with local anesthetics in dental blocks. Objective: This study aimed to assess the tissue
Anna Carolina Ratto Tempestini-Horliana +5 more
doaj +3 more sources
The root canal microbiome diversity and function. A whole-metagenome shotgun analysis [PDF]
Abstract Aim To evaluate the root canal microbiome composition and bacterial functional capability in cases of primary and secondary apical periodontitis utilizing whole‐metagenome shotgun sequencing. Methodology Twenty‐two samples from patients with primary root canal infections, and 18 samples obtained from previously treated teeth currently ...
Costalonga, Massimo
core +2 more sources
Hyalase in Dermatology: Applications Beyond Filler Management. [PDF]
ABSTRACT Background Hyaluronic acid (HA) is a key extracellular matrix component in the skin. Hyaluronidase is an enzyme that breaks down HA into monosaccharides. The FDA has approved this enzyme for hypodermoclysis, drug absorption enhancement, and subcutaneous urography.
Hasanzadeh S +6 more
europepmc +2 more sources
CEMIP (HYBID, KIAA1199): structure, function and expression in health and disease
Cell migration‐inducing protein, also called CEMIP, is a protein involved in the depolymerisation of hyaluronic acid (HA), a major component of the extracellular matrix (ECM). In this viewpoint, we discuss the main scientific evidence regarding CEMIP structure, function, role and expression, and we attempt to cast light on a protein that modulates the ...
Sofia Spataro +9 more
wiley +1 more source
Single‐amplified genomes reveal most streamlined free‐living marine bacteria
Abstract Evolutionary adaptations of prokaryotes to the environment sometimes result in genome reduction. Our knowledge of this phenomenon among free‐living bacteria remains scarce. We address the dynamics and limits of genome reduction by examining one of the most abundant bacteria in the ocean, the SAR86 clade.
Juan J. Roda‐Garcia +4 more
wiley +1 more source
By using a genetically modified mouse model and viral tracing approaches, we mapped both the anterograde and the retrograde projections of a subpopulation of neurons in the anterior paraventricular thalamic nucleus, molecularly defined by the expression of glucokinase (GckaPVT).
Sevasti Gaspari +4 more
wiley +1 more source
Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cells [PDF]
Docetaxel has been the standard first-line therapy in metastatic castration resistant prostate cancer. The survival benefit is, however, limited by either primary or acquired resistance.
AM Yvon +35 more
core +4 more sources
Cardioprotective factors against myocardial infarction selected in vivo from an AAV secretome library [PDF]
Therapies for patients with myocardial infarction and heart failure are urgently needed, in light of the breadth of these conditions and lack of curative treatments.
Bortolotti, Francesca +13 more
core +1 more source
Molecular mechanisms of toxicity of silver nanoparticles in zebrafish embryos. [PDF]
addresses: Biosciences, College of Life and Environmental Sciences, Geoffrey Pope Building, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK. r.van-aerle@exeter.ac.uktypes: Journal Article; Research Support, Non-U.S.
Agarwal D. P. +56 more
core +1 more source
The salivary secretome of the biting midge, Culicoides sonorensis [PDF]
Culicoides biting midges (Diptera: Ceratopogonidae) are hematophagous insects with over 1400 species distributed throughout the world. Many of these species are of particular agricultural importance as primary vectors of bluetongue and Schmallenberg ...
Barbara S. Drolet, Christopher J. Lehiy
core +2 more sources

