Results 41 to 50 of about 5,447 (121)

αVβ5 and CD44 Are Oxygen‐Regulated Human Embryonic Stem Cell Attachment Factors

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
Human embryonic stem cells (hESCs) have great potential for clinical therapeutic use. However, relatively little is known of the mechanisms which dictate their specificity of adhesion to substrates through adhesion proteins including integrins. Previous observations demonstrated enhanced clonogenicity in reduced oxygen culture systems.
Deepak Kumar, Saniya Gupta, Ying Yang, Nicholas R. Forsyth, Louise E. Glover   +4 more
wiley   +1 more source

From Genetics to Genomics of Epilepsy

Neurology Research International, Volume 2012, Issue 1, 2012., 2012
The introduction of DNA microarrays and DNA sequencing technologies in medical genetics and diagnostics has been a challenge that has significantly transformed medical practice and patient management. Because of the great advancements in molecular genetics and the development of simple laboratory technology to identify the mutations in the causative ...
Silvio Garofalo, Marisa Cornacchione, Alfonso Di Costanzo, Alexander Rotenberg   +3 more
wiley   +1 more source

Incidence of Blackleg in Beef Cattle and Implications of Regional Differences [PDF]

, 2021
Blackleg is an acute, fatal disease that has been afflicting cattle since the late 1800’s. It is caused by the anaerobic, spore-forming bacteria Clostridium chauvoei. This disease is characterized by swelling in areas like the legs, hips, chest, and back,
Henrich, Callie L
core   +1 more source

Biochips for Regenerative Medicine: Real-time Stem Cell Continuous Monitoring as Inferred by High-Throughput Gene Analysis [PDF]

, 2011
Regenerative medicine is a novel clinical branch aiming at the cure of diseases by replacement of damaged tissues. The crucial use of stem cells makes this area rich of challenges, given the poorly understood mechanisms of differentiation.
Christine Nardini, Giovanna del Vecchio, Giovanni de Micheli, Laura Calzà, Lisha Zhu, Sandro Carrara, Yuanhua Liu   +6 more
core   +4 more sources

Current and Emerging Bladder Cancer Urinary Biomarkers

The Scientific World Journal, Volume 11, Issue 1, Page 1103-1112, 2011., 2011
Bladder cancer continues to be one of the most common malignancies. Those who have been already diagnosed are at high risk for recurrence, especially if the pathology demonstrates high‐grade disease. Diagnosis and surveillance is reliant on invasive evaluation with cystoscopy.
Justin Parker, Philippe E. Spiess, Karim Kader   +2 more
wiley   +1 more source

ASGS: an alternative splicing graph web service [PDF]

, 2006
Alternative transcript diversity manifests itself a prime cause of complexity in higher eukaryotes. The Alternative Splicing Graph Server (ASGS) is a web service facilitating the systematic study of alternatively spliced genes of higher eukaryotes by ...
Bollina, Durgaprasad, Lee, Bernett T. K., Ranganathan, Shoba, Tan, Tin Wee   +3 more
core   +3 more sources

Consolidation, Systematic Appraisal and Comparison of Guideline Recommendations Regarding Management of Chronic Pain: Protocol for a Digital Chronic Pain Recommendation Map

Clinical and Public Health Guidelines, Volume 2, Issue 4, October 2025.
ABSTRACT Introduction Chronic pain affects 1 in 5 adults and children globally; however, management remains highly variable and low value care is common. Inconsistent recommendations among clinical practice guidelines for management of chronic pain contribute to suboptimal patient management.
Andrea J. Darzi, Kian Torabiardakani, Gonzalo Bravo‐Soto, Daniela Montalva‐Romero, Rachel J. Couban, Lynn Cooper, Stacey Ritz, Jaris Swidrovich, Ivan D. Florez, Vivian Welch, Gordon H. Guyatt, Holger J. Schünemann, Jason W. Busse, on behalf of the Chronic Pain RecMap Collaborative, Ahmad Firas Khalid, Abhimanyu Sud, Alfonso Iorio, Anaïs Lacasse, Andrew Thomas, Artur Nowak, Bart Dietl, Behnam Sadeghirad, Cyd Courchesne, Dena Zeraatkar, Edoardo Aromataris, Elaine Harrow, Farid Foroutan, Fei Yutong, Gabriel Rada, Glen Hazlewood, Hugo Massé‐Alarie, Jennifer Petkovic, Justyna Litynska, Keven Phinney, Lawrence Mbuagbaw, Li Wang, Lisa Graves, Luc J. Hébert, Marc‐André Blanchette, Peter Tugwell, Rebecca Morgan, Jean‐Sebastien Roy, Thomas Piggott, Trevor Jenvenne, Yaolong Chen, Ying Zhang, Zachary Munn, Zoe Jordan, Rana Yamout   +48 more
wiley   +1 more source

Repeated intratracheal instillation of whole‐cigarette smoke condensate to assess lung damage in a rat model

Environmental Toxicology, Volume 39, Issue 4, Page 2304-2315, April 2024.
Abstract Cigarette smoke induces an inflammatory response in the lungs by recruiting inflammatory cells, leading to lung diseases such as lung cancer, chronic obstructive pulmonary disease, and pulmonary fibrosis. Existing inhalation exposure methods for assessing the adverse effects of cigarette smoke require expensive equipment and are labor ...
Jinhee Kim, Yoon Cho, Gi‐Jun Oh, Hae‐Bin Park, Mi Jin Yang, Chul‐Min Park, Yong‐Hyun Kim, Kyung‐Chul Choi, Ryeo‐Eun Go, Min‐Seok Kim   +9 more
wiley   +1 more source

Unveiling the cancer-fighting potential of Rheum species (Rhubarb): Phytochemistry, ethnopharmacology, and mechanistic insights into the anticancer effects of key anthraquinones

Phytomedicine Plus
Background: Rhubarb (Rheum spp.) has been cultivated for over 5,000 years for both medicinal and culinary purposes. Renowned in traditional and modern medicine, it offers a range of therapeutic benefits.
Umer Majeed Khaja, Chirag Chopra, Amit Sehgal, Reena Singh, Showkat Ahmad Ganie   +4 more
doaj   +1 more source

Hyaluronic acid production in Streptococcus equi species [PDF]

, 2020
Hyaluronic acid (HA) is a glycosaminoglycan which exists ubiquitously in all organisms where it possesses a range of important functions. Due to the rheological properties and biocompatibility of HA solutions, it has been employed in a variety of ...
Milligan, Robyn
core