Uterine Gene Expression in the Live-Bearing Lizard, Chalcides ocellatus, Reveals Convergence of Squamate Reptile and Mammalian Pregnancy Mechanisms [PDF]
, 2012 Although the morphological and physiological changes involved in pregnancy in live-bearing reptiles are well studied, the genetic mechanisms that underlie these changes are not known.
Adams +116 more
core +2 more sources
Global Gene Expression Profiles of Subcutaneous Adipose and Muscle from Glucose-Tolerant, Insulin-Sensitive, and Insulin-Resistant Individuals Matched for BMI [PDF]
, 2011 OBJECTIVE - To determine altered gene expression profiles in subcutaneous adipose and skeletal muscle from nondiabetic, insulin-resistant individuals compared with insulin-sensitive individuals matched for BMI. RESEARCH DESIGN AND METHODS - A total of 62
Das, Swapan K. +5 more
core +3 more sources
Application of a Novel Algorithm for Expanding Newborn Screening for Inherited Metabolic Disorders across Europe [PDF]
, 2022 Inherited metabolic disorders (IMDs) are mostly rare, have overlapping symptoms, and can be devastating and progressive. However, in many disorders, early intervention can improve long-term outcomes, and newborn screening (NBS) programmes can reduce ...
Burlina, A +9 more
core
Molecular identification of hyaluronate lyase, not hyaluronidase, as an intrinsic hyaluronan-degrading enzyme in Clostridium perfringens strain ATCC 13124. [PDF]
Sci Rep日和見病原性ウェルシュ菌のヒアルロン酸分解機構 --抗菌剤開発への展開 --. 京都大学プレスリリース. 2024-10-23.Clostridium perfringens, an opportunistic pathogen, produces mu-toxin hyaluronidases including endo-β-N-acetylglucosaminidases (Nags) as a virulence invasion factor.
Kumon T, Oiki S, Hashimoto W.
europepmc +3 more sources
Circadian and light-driven regulation of rod dark adaptation [PDF]
, 2015 Continuous visual perception and the dark adaptation of vertebrate photoreceptors after bright light exposure require recycling of their visual chromophore through a series of reactions in the retinal pigmented epithelium (RPE visual cycle). Light-driven
Corbo, Joseph C +3 more
core +2 more sources
A comparison of 1% ropivacaine efficacy when associated or not with hyaluronidase in peribulbar anaesthesia in cataract surgery [PDF]
, 2015 Purpose: To evaluate the onset time and quality of peribulbar anesthesia with 1% ropivacaine associated or not with hyaluronidase 100 tru/ml for cataract extraction.
Arieta, Carlos Eduardo Leite +4 more
core +1 more source
Characterisation of the PrtM maturase of Streptococcus equi; a proven virulence factor in strangles [PDF]
Streptococcus equi subspecies equi (S. equi) is the pathogen responsible for the prevalent and highly contagious equine disease called strangles. Strangles has been reported worldwide as a cause of a high level of animal suffering and economic loss.
Ikolo, Felicia
core
Transcriptomic Characterization of Temperature Stress Responses in Larval Zebrafish [PDF]
, 2012 Temperature influences nearly all biochemical, physiological and life history activities of fish, but the molecular mechanisms underlying the temperature acclimation remains largely unknown.
A Aranda +68 more
core +4 more sources
Assessment of genes involved in lysosomal diseases using the ClinGen clinical validity framework [PDF]
Lysosomal diseases (LDs) are a heterogeneous group of rare genetic disorders that result in impaired lysosomal function, leading to progressive multiorgan system dysfunction.
Bali, Deeksha +17 more
core +2 more sources
Genetic and Environmental Factors Suggest that Dietary Fatty Acid Content, Lipid Metabolism, and Bone Properties are Key Regulators of Myeloid Progenitor Cell Frequency [PDF]
, 2010 Acute myelogenous leukemia (AML) and its precursors are the result of the dysregulation of hematopoiesis. Hematopoiesis proceeds in a stepwise manner, beginning with hematopoietic stem cells, continuing to develop into various stages of progenitor cells,
Varney, Melinda E.
core +1 more source