Results 91 to 100 of about 2,148,425 (298)

A Hybrid Denotational Semantics for Hybrid Systems [PDF]

, 2008
In this article, we present a model and a denotational semantics for hybrid systems. Our model is designed to be used for the verification of large, existing embedded applications. The discrete part is modeled by a program written in an extension of an imperative language and the continuous part is modeled by differential equations.
Olivier Bouissou, Matthieu Martel
openaire   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Thermal Sight: A Position‐Sensitive Detector for a Pinpoint Heat Spot

Small Science
Precise positioning is a never‐ending goal in both fundamental science and technology. Recent decades of advancements in high‐precision position detection have predominantly relied on photoelectric effects for light detection in semiconductors. Herein, a
Jun Peng, Pai Zhao, Rakshith Venugopal, Kristian Deneke, Stefanie Haugg, Robert Blick, Robert Zierold   +6 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Comparative transcriptome analysis reveals the impact of daily temperature difference on male sterility in photo-thermo-sensitive male sterile wheat

BMC Genomics
Background Photo-thermo-sensitive male sterility (PTMS), which refers to the male sterility triggered by variations in photoperiod and temperature, is a crucial element in the wheat two-line hybrid system. The development of safe production and efficient
Fuqiang Niu, Zihan Liu, Yongjie Liu, Jianfang Bai, Tianbao Zhang, Shaohua Yuan, Xiucheng Bai, Changping Zhao, Fengting Zhang, Hui Sun, Liping Zhang, Xiyue Song   +11 more
doaj   +1 more source

Hybrid bases in graphs [PDF]

In this paper we introduce a new concept, that of hybrid base, which is a maximal circuitless and cutsetless subset of a graph. Although this concept of simultaneous circuitlessness and cutsetlessness has been used in proofs of some theorems in so called
Gibbons, Alan, Novak, Ladislav
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Brassinosteroid and jasmonic acid pathways mediate the effect of high temperature on the outcrossing rate of photo-thermo-sensitive genic male-sterile rice lines

BMC Plant Biology
Background The development and widespread adoption of hybrid rice have significantly contributed to global food security. However, the relatively high cost of hybrid seeds remains a limiting factor for its broader application.
Duo Lan, Pengpeng Fang, Li Zhang, Jia Zeng, Wuhan Zhang, Qiang He, Xiaolin Li, Ying Lv, Huafeng Deng, Fu Shu, Pingyong Sun   +10 more
doaj   +1 more source

SRAM and Mixed-Signal Logic With Noise Immunity in 3-nm Nano-Sheet Technology

IEEE Open Journal of the Solid-State Circuits Society
A modular 4.26 Mb SRAM based on a 82 Kb/block structure with mixed signal logic is fabricated, characterized, and demonstrated with full functionality in a 3-nm nanosheet (NS) technology.
Rajiv V. Joshi, J. Frougier, Alberto Cestero, Crystal Castellanos, Sudipto Chakraborty, Carl Radens, M. Silvestre, S. Lucarini, I. Ahsan, E. Leobandung   +9 more
doaj   +1 more source