Results 81 to 90 of about 850,758 (269)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Brassinosteroid and jasmonic acid pathways mediate the effect of high temperature on the outcrossing rate of photo-thermo-sensitive genic male-sterile rice lines

BMC Plant Biology
Background The development and widespread adoption of hybrid rice have significantly contributed to global food security. However, the relatively high cost of hybrid seeds remains a limiting factor for its broader application.
Duo Lan, Pengpeng Fang, Li Zhang, Jia Zeng, Wuhan Zhang, Qiang He, Xiaolin Li, Ying Lv, Huafeng Deng, Fu Shu, Pingyong Sun   +10 more
doaj   +1 more source

SRAM and Mixed-Signal Logic With Noise Immunity in 3-nm Nano-Sheet Technology

IEEE Open Journal of the Solid-State Circuits Society
A modular 4.26 Mb SRAM based on a 82 Kb/block structure with mixed signal logic is fabricated, characterized, and demonstrated with full functionality in a 3-nm nanosheet (NS) technology.
Rajiv V. Joshi, J. Frougier, Alberto Cestero, Crystal Castellanos, Sudipto Chakraborty, Carl Radens, M. Silvestre, S. Lucarini, I. Ahsan, E. Leobandung   +9 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Comparative transcriptome analysis reveals the impact of daily temperature difference on male sterility in photo-thermo-sensitive male sterile wheat

BMC Genomics
Background Photo-thermo-sensitive male sterility (PTMS), which refers to the male sterility triggered by variations in photoperiod and temperature, is a crucial element in the wheat two-line hybrid system. The development of safe production and efficient
Fuqiang Niu, Zihan Liu, Yongjie Liu, Jianfang Bai, Tianbao Zhang, Shaohua Yuan, Xiucheng Bai, Changping Zhao, Fengting Zhang, Hui Sun, Liping Zhang, Xiyue Song   +11 more
doaj   +1 more source

OsLAP6/OsPKS1, an orthologue of Arabidopsis PKSA/LAP6, is critical for proper pollen exine formation

Rice, 2017
Background Male fertility is crucial for rice yield, and the improvement of rice yield requires hybrid production that depends on male sterile lines.
Ting Zou, Qiao Xiao, Wenjie Li, Tao Luo, Guoqiang Yuan, Zhiyuan He, Mingxing Liu, Qiao Li, Peizhou Xu, Jun Zhu, Yueyang Liang, Qiming Deng, Shiquan Wang, Aiping Zheng, Lingxia Wang, Ping Li, Shuangcheng Li   +16 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

EdemaFlex: textile-based soft-robotic platform toward personalized hand edema therapy

npj Flexible Electronics
Hand edema hinders mobility and quality of life, yet prevailing solutions—manual lymphatic drainage or bulky pneumatic devices—are costly, clinic-bound, and rarely personalized.
Seonyoung Youn, Arhan Choudhury, Pin-Sung Ku, Wenyi Fu, Margaret Tsai, Mahika Rathod, Alyssa Pelak, Joan Stilling, Hsin-Liu (Cindy) Kao   +8 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source