Results 101 to 110 of about 1,474,022 (242)

Photothermal ablation of pancreatic cancer cells with hybrid iron-oxide core gold-shell nanoparticles

, 2013
Yang Guo,1 Zhuoli Zhang,1 Dong-Hyun Kim,1,5 Weiguo Li,1 Jodi Nicolai,1 Daniel Procissi,1 Yi Huan,2 Guohong Han,3 Reed A Omary,1,4,5 Andrew C Larson1,4,5 1Department of Radiology, Northwestern University, Chicago, IL, USA; 2Department of Radiology, Xijing
Kim DH, Li W, Nicolai J, Guo Y, Zhang Z, Procissi D, Huan Y, Han G, Larson AC, Omary RA   +9 more
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Rapid and mask-less laser-processing technique for the fabrication of microstructures in polydimethylsiloxane

, 2014
We report a rapid laser-based method for structuring polydimethylsiloxane (PDMS) on the micron-scale. This mask-less method uses a digital multi-mirror device as a spatial light modulator to produce a given spatial intensity pattern to create arbitrarily
Sones, C.L., Mills, B., Butement, J., Feinäugle, M., Mosayyebi, Ali, Katis, I.N., Eason, R.W.   +6 more
core   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

The clinical effectiveness and cost-effectiveness of ablative therapies in the management of liver metastases: systematic review and economic evaluation [PDF]

, 2014
Background: Many deaths from cancer are caused by metastatic burden. Prognosis and survival rates vary, but survival beyond 5 years of patients with untreated metastatic disease in the liver is rare.
Breen, D., George, S., Joanna Picot, Steve George, Colquitt, Jillian, Mendes, Diana, Emma Loveman, Primrose, John, Clegg, Andrew J., Picot, J., John Primrose, Cunningham, David, Andrew J Clegg, Ruters, Theo, Theo Ruers, Colquitt, J.L., Cunningham, D., Moore, E., Ruers, T., Jones, Jeremy, Jeremy Jones, Picot, Joanna, Breen, David J., Jillian L Colquitt, Primrose, J.N., Clegg, Andrew, Graeme Poston, Loveman, Emma, Emily Moore, Moore, Emily, Diana Mendes, David J Breen, Poston, G., Poston, Graeme, George, Steve, David Cunningham   +35 more
core   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Sub-debris melt rates on southern Inylchek Glacier, central Tian Shan [PDF]

, 2008
Melt rates of glacier surfaces are strongly influenced by the existence of a debris cover. Dependent on thickness and other physical parameters the debris layer can enhance or reduce ablation as compared to bare ice conditions.
Lambrecht, Astrid, Wilfried Hagg, Christoph Mayer, Helm, Achim, Astrid Lambrecht, Mayer, Christoph, Hagg, Wilfried, Achim Helm   +7 more
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Staged introduction of a first-in-human concomitant robotic liver resection and cone-beam CT-guided percutaneous liver ablation in a hybrid operating room (HARMONY): an IDEAL stage 0/1 study

BMJ Surgery, Interventions, & Health Technologies
Objectives To perform the first-in-human concomitant robotic liver resection and cone-beam CT (CBCT)-guided ablation in a hybrid operating room (HARMONY).Design IDEAL stage 0/1 study outlining the preparatory steps and outcomes of the first-in-human ...
Rutger-Jan Swijnenburg, Gabriela Pilz da Cunha, Hannah H Schulz, Tijs J Hoogteijling, Maarten LJ Smits, Katrin Stoecklein   +5 more
doaj   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source