Results 81 to 90 of about 1,474,022 (242)

Noninvasive release of tendons using MRI guided focused ultrasound: a hybrid therapy using long-pulse focused ultrasound followed by thermal ablation

International Journal of Hyperthermia
Introduction Magnetic Resonance-guided Focused Ultrasound (MRgFUS) thermal ablation is an effective noninvasive ultrasonic therapy to disrupt in vivo porcine tendon but is prone to inducing skin burns.
William Chu Kwan, Imogen den Otter-Moore, Ari Partanen, Karolina Piorkowska, Unni Narayanan, Adam C. Waspe, James M. Drake   +6 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Magnetocardiographic demonstration of complex ventricular preexcitation resulting in ablation failure

, 2013
The Wolff-Parkinson-White (WPW) syndrome affects 1 to 3 persons per 1000. Catheter ablation (CA) is nowadays proposed as the preferred therapy (with success in more than 90% of cases) and ECG is the most used non-invasive method for classification and ...
Brisinda, Donatella, Sorbo, Anna Rita, Venuti, Angela, Fenici, Riccardo   +3 more
core   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Hybrid atrial fibrillation ablation in patients with persistent atrial fibrillation or failed catheter ablation [PDF]

, 2019
Background Combined 'hybrid' thoracoscopic and percutaneous atrial fibrillation (AF) ablation is a strategy used to treat AF in patients with therapy-resistant symptomatic AF.
Blaauw, Y., Rienstra, M.; id_orcid, Rienstra, M., Klinkenberg, T. J., van Gelder, I. C., Mariani, M. A., Al-Jazairi, M. I. H.   +6 more
core   +2 more sources

Enhanced Precision in the Convergent Procedure for Persistent Atrial Fibrillation Using Real‐Time Intraoperative 3D Electrophysiological Mapping

Clinical Case Reports
Real‐time intraoperative electrophysiological mapping significantly enhances the precision and efficiency of ablations in epicardial ablation (Convergent procedure) for persistent atrial fibrillation.
Ujjawal Kumar, Usman Aslam, Leslie Epting, Anthony Cooper, Alyssa Abraham, Zain Khalpey   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Meteorology and surface energy fluxes in the 2005–2007 ablation seasons at the Miage debris-covered glacier, Mont Blanc Massif, Italian Alps [PDF]

, 2010
During the 2005–2007 June–September ablation seasons, meteorological conditions were recorded on the lower and upper parts of the debris‐covered ablation zone of Miage Glacier, Italy. In 2005, debris temperature and subdebris ice melt were also monitored
Mihalcea, Claudia, Diolaiuti, Guglielmina, G.A. Diolaiuti, Brock, Ben W., Kirkbride, Martin P., M. Kirkbride, C.E. Mihalcea, Cutler, Mark E. J.; id_orcid, C. Smiraglia, M. E. J. Cutler, Cutler, Mark, Brock, Benjamin, Kirkbride, Martin, Smiraglia, Claudio, B. W. Brock   +14 more
core   +1 more source

Spatial displacement on three-dimensional maps caused by rhythm differences in premature ventricular contraction ablation

Indian Pacing and Electrophysiology Journal
Introduction: Three-dimensional (3D) maps are useful for premature ventricular contraction (PVC) ablation. However, positional information changes compared with sinus rhythm when PVCs appear, rendering ablation difficult.
Yusuke Sakamoto, Hiroyuki Osanai, Yoshihito Nakashima, Hiroshi Asano   +3 more
doaj   +1 more source