Results 41 to 50 of about 3,645,737 (298)

A HYBRID ALGORITHM FOR THE ADWORDS PROBLEM

open access: yesJournal of the Operations Research Society of Japan, 2023
Summary: The adwords problem (or the ad-auctions problem) is an online problem which decides allocations of advertisements to search words. The search words arrive one-by-one and a search engine decides what advertisement to display upon arrival of each search word.
Moriyama, Iori, Mizuno, Shinji
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A Novel Hybrid Harris Hawks Optimization for Color Image Multilevel Thresholding Segmentation

open access: yesIEEE Access, 2019
Multilevel thresholding has got more attention in recent years with various successful applications. However, the implementation becomes more and more complex and time-consuming when the number of thresholds is high, and color images which contain more ...
Xiaoli Bao, Heming Jia, Chunbo Lang
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Analysis of hybrid Nd:Yag laser-MAG arc welding processes. [PDF]

open access: yes, 2011
In the hybrid laser-arc welding process, a laser beam and an electric arc are coupled in order to combine the advantages of both processes: high welding speed, low thermal load and high depth penetration thanks to the laser; less demanding on joint ...
F. Coste   +9 more
core   +1 more source

Efficient daily electricity demand prediction with hybrid deep-learning multi-algorithm approach [PDF]

open access: yes, 2023
Predicting electricity demand (\u1d43a) is crucial for electricity grid operation and management. In order to make reliable predictions, model inputs must be analyzed for predictive features before they can be incorporated into a forecast model.
Sujan Ghimire   +7 more
core   +1 more source

Towards a Hybrid Metabolic Algorithm [PDF]

open access: yes, 2006
During recent years stochastic algorithms have deserved much attention from the computational biology research communities. In this paper we derive a hybrid version of the formerly known Metabolic Algorithm that is enriched with stochastic features, whose impact on the dynamics of the system is especially prominent when the amount of metabolite becomes
Luca Bianco, Federico Fontana
openaire   +4 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A hybrid CFGTSA based approach for scheduling problem: a case study of an automobile industry [PDF]

open access: yes, 2006
In the global competitive world swift, reliable and cost effective production subject to uncertain situations, through an appropriate management of the available resources, has turned out to be the necessity for surviving in the market. This inspired the
Vikas Kumar   +13 more
core   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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