Results 71 to 80 of about 28,002,475 (294)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Analysis on hybrid fractals

Communications on Pure and Applied Analysis, 2020
41 pages, 25 figures, 4 ...
Ruiz, Patricia Alonso, Chen, Yuming, Gu, Haotian, Strichartz, Robert S., Zhou, Zirui   +4 more
openaire   +3 more sources

Formal Verification of Analog and Mixed Signal Circuit [PDF]

Jisuanji gongcheng, 2016
For the low fidelity and nonnormative description of formal modeling in Analog and Mixed Signal(AMS) circuit,a formal modeling method is proposed based on nodal analysis of Kirchhoff’s Current Law(KCL).An extension to Computation Tree Logic(CTL) formula
YANG Shihan,WU Jinzhao,DING Guanghong,QIN Donghong
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Special issue on hybrid fuzzy models

, 2010
This special issue is composed of five papers addressing different topics in current developments of Hybrid Fuzzy Models. The issue originated from presentations at the 8th International Conference on Hybrid Intelligent Systems that was held in Barcelona,
García López, Salvador, Caballé Llobet, Santi, Benítez, José María, Juan Pérez, Ángel Alejandro   +3 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Hybrid Partial Least Squares-Structural Equation Modelling and Multi-Layer Perceptron for Predicting E-Participation Success in E-Government Services: Socio-Cultural Insights and Extended Validation

Journal of ICT
Although the Delone and McLean IS Success Model (D&M) can explain the phenomenon of e-participation success (EPS), the model was initially created in an e-commerce setting and thus neglects external factors related to e-government services.
Hapini Awang, Nur Suhaili Mansor, Muhammad Syafiq Mohd Pozi, Shehu Malami Sarkin Tudu, Isyaku Uba Haruna, Mazni Omar, Mazzlida Mat Deli   +6 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Hybrid sandwich panel with natural fibre composite intermediate layer: manufacturing process and significance analysis [PDF]

, 2013
Natural fiber reinforced plastic (NFRP) has drawn more attention as an alternative materials, particularly when dealing with the concept of green or sustainable building.
Fajrin, Jauhar, Zhuge, Yan, Bullen, Frank, Wang, Hao   +3 more
core  

Deep MCRan: Hybrid Analysis-Based Ransomware Detection Using Multi-Channel Data Fusion

IEEE Access
Ransomware has emerged as one of the most destructive cybersecurity threats, causing substantial financial losses and operational disruptions. Attackers increasingly employ obfuscation and evasion techniques to bypass traditional security mechanisms ...
Sibel Gulmez, Arzu Gorgulu Kakisim, Ibrahim Sogukpinar   +2 more
doaj   +1 more source