Results 51 to 60 of about 192,161 (313)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Journal of Materials Research and Technology, 2022 Hybrid laminated composites were fabricated from woven kenaf, woven polyester and polylactic acid (PLA) using the hot compression method. The hybrid composites consist of woven material as reinforcement having the fiber weight-matrix ratio of 40:60.
M.N.M. Azlin +3 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Nature CommunicationsUltrathin, broadband microwave absorbing materials (MAMs) are crucial for weight-sensitive and space-constrained applications. This study introduces the electromagnetic frequency dispersion coefficient (EFDC), a synergistic dielectric-magnetic parameter ...
Haoxu Si +6 more
doaj +1 more source
Effect of Glass Fiber Hybridization on the Behavior Under Impact of Woven Carbon Fiber/Epoxy Laminates [PDF]
, 2010 The low-velocity impact behavior was studied in hybrid laminates manufactured by RTM with woven carbon and glass (S2) fabrics. Specimens with different thicknesses and glass fiber content (from 0 to 21 vol.%) were tested with impact energies in the range
A. Enfedaque +6 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
UNIDIRECTIONAL HYBRID COMPOSITE OVERLOAD SENSORS [PDF]
, 2017 A purpose-designed, thin-ply interlayer glass/carbon hybrid composite overload sensor concept is presented, which can be used for structural health monitoring (SHM) of composite structures, with potential for safer operation in service.
Rev, T. +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Inorganic–organic nanocomposites of CdSe nanocrystals surface-modified with oligo- and poly(fluorene) moieties [PDF]
, 2011 We report a facile grafting-from strategy towards the synthesis of inorganic–organic composites of semiconductor nanocrystals and wide-bandgap polymers.
Adamczyk, Sylwia +12 more
core +1 more source