Results 81 to 90 of about 2,261,478 (345)

Investigation of mixed element hybrid grid-based CFD methods for rotorcraft flow analysis [PDF]

, 2010
Accurate first-principles flow prediction is essential to the design and development of rotorcraft, and while current numerical analysis tools can, in theory, model the complete flow field, in practice the accuracy of these tools is limited by various ...
Boschitsch, Alexander H., Brown, Richard, Lynch, C. Eric, Smith, Marlyn J., Whitehouse, Glen R.   +4 more
core  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Hybrid Projection Methods with Recycling for Inverse Problems [PDF]

arXiv, 2020
Iterative hybrid projection methods have proven to be very effective for solving large linear inverse problems due to their inherent regularizing properties as well as the added flexibility to select regularization parameters adaptively. In this work, we develop Golub-Kahan-based hybrid projection methods that can exploit compression and recycling ...
arxiv  

Public hybrid spaces as a component of contemporary cities [PDF]

, 2016
The main objectives of research work presented in the paper are: 1/Exploring the urban design solutions of public hybrid spaces in contemporary cities, which are the outstanding examples of expressive identity, 2/Carrying out the modern interpretation of
Pluta, Katarzyna
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Advances in efficient desalination technology of capacitive deionization for water recycling

Water Reuse, 2021
Available freshwater resources are becoming harder to obtain due to climate change, population growth, industrial development, and water pollution. The main technologies in the field of wastewater desalination include reverse osmosis, electrodialysis ...
Yuhao Tong, Shuang Zhou, Jun Zhou, Guanteng Zhang, Xiaolin Li, Chunxia Zhao, Pengyan Liu   +6 more
doaj   +1 more source

Formalization and Validation of Safety-Critical Requirements [PDF]

, 2010
The validation of requirements is a fundamental step in the development process of safety-critical systems. In safety critical applications such as aerospace, avionics and railways, the use of formal methods is of paramount importance both for ...
Alessandro Cimatti, Angelo Susi, Manuela Bujorianu, Marco Roveri, Michael Fisher, Stefano Tonetta   +5 more
core   +2 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Toward Zero-Emission Hybrid AC/DC Power Systems with Renewable Energy Sources and Storages: A Case Study from Lake Baikal Region

Energies, 2020
Tourism development in ecologically vulnerable areas like the lake Baikal region in Eastern Siberia is a challenging problem. To this end, the dynamical models of AC/DC hybrid isolated power system consisting of four power grids with renewable generation
Denis Sidorov, Daniil Panasetsky, Nikita Tomin, Dmitriy Karamov, Aleksei Zhukov, Ildar Muftahov, Aliona Dreglea, Fang Liu, Yong Li   +8 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source