Results 71 to 80 of about 1,562,908 (297)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Development and testing of a remote hybrid SMS/web-based perioperative messenger: A mixed-methods study

Digital Health
Background Perioperative messengers as tools for hospitals to communicate with patients’ loved ones during surgery have been described in form of pagers, SMS, email, and apps.
Mojca Hriberšek, Daniel Laxar, Fabian Peter Hammerle, Stefan Ulbing, Anna Teufel, Stefan Bartos, Nikola Gauß, Martin Niederle, Oliver Kimberger, Eva Schaden   +9 more
doaj   +1 more source

Developing Clean Technology through Approximate Solutions of Mathematical Models [PDF]

, 2012
In this paper, the role of mathematical modeling in the development of clean technology has been considered. One method each for obtaining approximate solutions of mathematical models by ordinary differential equations and partial differential ...
Anake, T. A.
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Two-step hybrid numerical integrators for the solutions of highly oscillatory systems of ODEs with fixed step size

Scientific African
Collocation methods have shown great promise in developing numerical techniques for solving stiff and highly oscillatory problems in ordinary differential equations.
Dauda G. Yakubu, Joshau P. Chollom, Adelegan L. Momoh, Geoffrey M. Kumleng   +3 more
doaj   +1 more source

Evaluation of deterioration index in soil nutrients due to cultivation of different cocoa species in southwest Nigeria

Journal of Applied Sciences and Environmental Management, 2018
The study uses the index of soil deterioration to evaluate the soil nutrient status as a result of cultivating different species of cocoa in Idanre, Odigbo and Owo areas of Southwest Nigeria.
O.S. Afolayan, F.O. Oderinde
doaj   +1 more source

A QM/MM approach for the study of monolayer-protected gold clusters

, 2012
We report the development and implementation of hybrid methods that combine quantum mechanics (QM) with molecular mechanics (MM) to theoretically characterize thiolated gold clusters.
A Corma, A Venzo, A Warshel, AC Templeton, AK Rappé, ASK Hashmi, CJ Zhong, CM Aikens, DT Miles, F Weigend, G Henkelman, H Qian, I Garzón, J Akola, JF Parker, John A. Montgomery, José A. Gascón, JR Cheeseman, JTv Wijngaarden, L Fabris, M Dasog, M Haruta, MS Devadas, MW Heaven, MZ Zhu, NV Perera, O Lopez-Acevedo, PD Jadzinsky, RFW Bader, S Dapprich, Sandipan Banerjee, T Vreven, WD Cornell   +32 more
core   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Factors Influencing Success of Wind-Diesel Hybrid Systems in Remote Alaska Communities: Results of an Informal Survey [PDF]

, 2011
In 2008 the Alaska State Legislature created and funded the Renewable Energy Fund. As a result of this available funding, the number of wind-diesel hybrid power systems is increasing dramatically in rural Alaska.
Fay, Ginny, Udovyk, Nataliya
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source