Results 51 to 60 of about 1,562,908 (297)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The role of corporate social responsibility and soft law options in the protection of migrant workers' interests in host countries: the case of Malaysia [PDF]
, 2012 This article examines the potential for corporate social responsibility (CSR) and other soft law initiatives in generating change for blue-collar migrant workers in the Malaysian workplace.
Sundra-Karean, Vanitha +1 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
National Science Open, 2023 In order to increase the renewable energy penetration for building and industrial energy use in industrial parks, the energy supply system requires transforming from a centralized energy supply mode to a distributed + centralized energy supply mode.
Guo Jiacheng +4 more
doaj +1 more source
Public hybrid spaces as a component of contemporary cities [PDF]
, 2016 The main objectives of research work presented in the paper are: 1/Exploring the urban design solutions of public hybrid spaces in contemporary cities, which are the outstanding examples of expressive identity, 2/Carrying out the modern interpretation of
Pluta, Katarzyna
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
INFLUENCE OF HYBRID EDUCATION TRENDS ON THE TEACHING METHODS OF MEDICAL STUDENTS
Russian Journal of Education and Psychology, 2023 The article discusses innovative learning models, as well as trends in the development of hybrid education, including alternative forms of education, and its impact on the teaching methods of medical university students.
Anna A. Voloshenko, Natalia V. Khomovich
doaj +1 more source
CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. [PDF]
, 2017 Broad-scale protein-protein interaction mapping is a major challenge given the cost, time, and sensitivity constraints of existing technologies. Here, we present a massively multiplexed yeast two-hybrid method, CrY2H-seq, which uses a Cre recombinase ...
Bartlett, Anna +12 more
core +2 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Advances in Difference Equations, 2020 In this paper, the development of new hybrid group iterative methods for the numerical solution of a two-dimensional time-fractional cable equation is presented.
Fouad Mohammad Salama +2 more
doaj +1 more source