Results 41 to 50 of about 1,823,632 (294)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Active Power Filters Under Marketing Aspect [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2013
This paper presents some active power filters and their solutions with equipment based on power electronics. A short marketing study concerning the shunt, hybrid and series active power filters isdescribed showing their main schemes, and principles of ...
SILAGHI Helga   +3 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Advanced Universal Hybrid Power Filter Configuration for Enhanced Harmonic Mitigation in Industrial Power Systems: A Field-Test Approach

open access: yesEnergies
Power quality is a critical concern for large-scale industrial operations, necessitating advanced power conditioning equipment to maintain optimal performance and efficiency.
Mohsen Davoodi   +3 more
doaj   +1 more source

Hybrid Power Filter Based on a Six-Switch Two-Leg Inverter

open access: yesEletrônica de Potência, 2014
Hybrid power filters (HPFs) are considered an attractive solution to overcome the problem of current harmonics generated by nonlinear loads. They mix low power rating active filters with passive filters, but many of these HPF topologies have a great ...
Leonardo R. Limongi   +4 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Implementation of unknown parameter estimation procedure for hybrid and discrete non‐linear systems

open access: yesIET Radar, Sonar & Navigation
The application of the hybrid extended Kalman filter (HEKF), hybrid unscented Kalman filter (HUKF), hybrid particle filter (HPF), and hybrid extended Kalman particle filter (HEKPF) is discussed for hybrid non‐linear filter problems, when prediction ...
Mahdi Razm‐Pa
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Learning hybrid part filters for scene recognition

open access: yes, 2012
. This paper introduces a new image representation for scene recognition, where an image is described based on the response maps of object part filters.
Yu-gang Jiang   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy