Results 221 to 230 of about 139,280 (294)

Computational identification of lineage-committed precursors in mammalian organogenesis reveals a novel hematopoietic enhancer regulating Bhlhe41 expression. [PDF]

Brief Bioinform
Jin L, Han Z, Hannah R, Shao H, Huang J, Wang S, Zhang W, Lin J, Sun K, Yu Y.   +9 more
europepmc   +1 more source

Integrative genomic and spatial transcriptomic analysis elucidates the oligodendrocyte‐mediated etiology of epileptic cortical thinning

Epilepsia Open, EarlyView.
Abstract Objective Focal epilepsy is characterized by progressive cortical thinning, particularly within limbic structures; however, whether this atrophy reflects acquired seizure‐induced damage or shared genetic predisposition remains unresolved. Methods We integrated genome‐wide association study (GWAS) summary statistics from the ILAE Consortium ...
Dingyuan Zhang, Qianqian Zhang, Guangming Li, Lingting Yu, Yanling Ma, Xiaoli Hong, Yujie Kui, Shanshan Cai, Jianguang Sun, Zechao Zhu   +9 more
wiley   +1 more source

Incomplete lineage sorting shaped mixed traits during a colobine primate radiation. [PDF]

Proc Natl Acad Sci U S A
Guo YQ, Wang Y, Garber PA, Li Y, Zhang R, Zhang C, Huang Z, Wu DD, Li BG, Cui L, Li B, Qi XG.   +11 more
europepmc   +1 more source

Artificial Intelligence in Ophthalmology: Current Status, Challenges, and Future Perspectives

Health Care Science, EarlyView.
Current research of artificial intelligence (AI) in ophthalmology. ABSTRACT Artificial intelligence (AI) is revolutionizing ophthalmology by providing innovative solutions for disease screening, diagnosis, personalized treatment, and the delivery of global healthcare services.
She Chongyang, Tao Yong
wiley   +1 more source

Comparative Genome Analysis of Illumina, Nanopore, and Hybrid Approaches: A Case Study of the Aquaculture Isolate 160P. [PDF]

Pathogens
Saticioglu IB, Bozkurt J, Duman M.
europepmc   +1 more source

Lineage rewiring in lung adenocarcinoma via HNF4α and NKX2-1 dynamics. [PDF]

Genes Dev
Feng A, Yermalovich A, Meyerson M.
europepmc   +1 more source

Open data phylometabolomics reveals turnover-dominated chemical divergence and clade-specific physicochemical regimes across angiosperms. [PDF]

Plant J
Carollo CA, Boaretto AG, Nocetti MC, Carollo ARH, Alves FM.   +4 more
europepmc   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source

Schizothoracinae in Plateau River Networks: Drainage History, Polyploid Genome Evolution, Multi-Omics Evidence Chains, and Conservation Units. [PDF]

Animals (Basel)
Cao Y, Wang N, Hu Q, Zhu X.
europepmc   +1 more source