Results 241 to 250 of about 139,280 (294)

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

open access: yesMed Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang   +12 more
wiley   +1 more source

Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo   +4 more
wiley   +1 more source

Osmotic signaling governs sunscreen biosynthesis to safeguard desert cyanobacteria against desiccation

open access: yesmLife, EarlyView.
Abstract Mycosporine‐like amino acids (MAAs) are natural sunscreens synthesized by a wide range of organisms. Although the induction of MAA production by ultraviolet radiation is well established, the signaling pathways involved and specific functions of MAAs under other stress conditions remain poorly understood.
Lei Zhao   +7 more
wiley   +1 more source

Biogeography and diversification patterns in the Irano‐Turanian biodiversity hotspots inferred from a molecular phylogeny of the subendemic Iris subgenus Scorpiris (Iridaceae)

open access: yesNordic Journal of Botany, EarlyView.
The Irano‐Turanian Floristic Region harbors a rich flora, but our understanding of the development of this diversity is limited by a lack of data on phylogenetic relationships and biogeographic patterns of endemic and more widespread plants. Hypotheses of in situ diversification versus allopatric diversification were tested using Iris subgen. Scorpiris,
Mona Salimbahrami   +4 more
wiley   +1 more source

Deciphering the soybean root rot pathogen Phytophthora sojae: Signaling pathways, transcriptional regulation, and effector biology

open access: yesNew Plant Protection, EarlyView.
This review highlights how Phytophthora sojae utilizes unconventional lineage‐specific signaling networks, including unique G protein‐coupled receptor fusions, expanded kinases, and rapidly evolving effectors, to infect soybeans. Understanding these divergent molecular paradigms reveals critical vulnerabilities in this destructive pathogen, offering ...
Min Qiu   +4 more
wiley   +1 more source

Islamic Public Administration in Practice: The Taliban's “Gender Apartheid” Governance in Afghanistan

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT This article analyzes the Taliban's post‐2021 governance model through the Islamic Public Administration (IPA) framework, focusing on justice, equality, and women's inclusion. It asks: (1) How does the Taliban's governance align with core IPA principles?
Parwiz Mosamim   +1 more
wiley   +1 more source

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