Results 101 to 110 of about 155,289 (268)

Investigating protein conformational ensembles by native mass spectrometry and complementary biophysical techniques—the case of α-synuclein

Frontiers in Biophysics
One of the challenges of modern structural biology is to account for protein structural dynamics. Intrinsically disordered proteins (IDPs), which do not fold spontaneously into a defined conformation, existing, instead, as highly heterogeneous ...
Stefania Brocca, Erika Ponzini, Erika Ponzini, Carlo Santambrogio, Rita Grandori, Rita Grandori   +5 more
doaj   +1 more source

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

Improving Support Vector Regression for Predicting Mechanical Properties in Low-Alloy Steel and Comparative Analysis

Mathematics
Low-alloy steel is widely employed in the aviation industry for its exceptional mechanical properties. These materials are frequently used in critical structural components such as aircraft landing gear and engine mounts, where a high strength-to-weight ...
Zhongyuan Che, Chong Peng
doaj   +1 more source

Examining the Interchangeability of Two Different Patient‐Reported Global Assessment Measures in an Observational Axial Spondyloarthritis Cohort

Arthritis Care &Research, EarlyView.
Objective The goal of this study was to determine if patient global assessment (PGA) scores reported by patients with axial spondyloarthritis (AxSpA) before the development of the AxSpA Disease Activity Score (ASDAS) can be used as a substitute for the global item of the ASDAS formula.
Connor Vershel, Seokhun Kim, Lianne S. Gensler, Matthew A. Brown, Michael H. Weisman, Mariko L. Ishimori, Michael Ward, John D. Reveille, Mark C. Hwang   +8 more
wiley   +1 more source

Optimized Machine Learning-Augmented Hybrid Empirical Models for AlGaN/GaN HEMTs: A Comprehensive Analysis

IEEE Access
Precise modeling of gallium nitride (GaN) high-electron mobility transistors (HEMTs) is vital for ensuring reliable and scalable RF circuit design, and efficient characterization of the device behavior.
Ahmad Khusro, Saddam Husain, Mohammad Hashmi   +2 more
doaj   +1 more source

Observer‐Based Adaptive Event‐Triggered Tracking Control for Fuzzy TS Systems With Premise Mismatch

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper presents an adaptive logistic event‐triggered observer‐based tracking controller for Takagi‐Sugeno fuzzy systems under constrained inputs and network delays. Leveraging a hybrid LMI and Secretary Bird Optimization approach, this strategy significantly minimizes communication overhead and computational burden while ensuring optimal reference ...
Oussama Djadane, Salama Makni, Mourad Kchaou, Ahmed El Hajjaji   +3 more
wiley   +1 more source

A Hybrid Approach for Predictive Control of Oil Well Production Using Dynamic System Identification and Real-Time Parameter Estimation

Computation
A significant part of modern natural sciences aims to establish a model-based approach to describe the behavior of physical systems and forecast their dynamics in different scenarios.
Anton Gryzlov, Eugene Magadeev, Muhammad Arsalan   +2 more
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

A physics-informed Bayesian data assimilation approach for real-time drilling tool lateral motion prediction

Frontiers in Mechanical Engineering
In this study, a Bayesian data assimilation method that fuses physics with motion sensor data is demonstrated to infer the dynamic states at points of interest on the bottomhole assembly (BHA) with proper uncertainty quantification.
Fei Song, Kevin Shi, Ke Li, Amine Mahjoub, Sepand Ossia, Ives Loretz, Robson Serafim   +6 more
doaj   +1 more source

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

Advanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora, Tales V. Lisbôa, Axel Spickenheuer, Rogério J. Marczak, Jakson M. Vassoler   +4 more
wiley   +1 more source