Results 91 to 100 of about 143,062 (268)
Qinghai Lake, the largest endorheic saline lake in China, has undergone a pronounced hydrological regime shift from a multi-decadal decline to a rapid post-2004 recovery, reflecting strong hydroclimatic non-stationarity in the northeastern Tibetan ...
Pengfei Hou +9 more
doaj +1 more source
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source
Hybrid mechanistic–machine learning PK/PD models with digital biomarkers: from cage to clinic
BackgroundPharmacometric PK/PD models remain central to dose selection for first-in-human studies, therapeutic drug monitoring, and animal-to-human extrapolation of exposure–response relationships, but modern datasets, including digital biomarkers from ...
Szczepan W. Baran +3 more
doaj +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
AbstractHybrid models that combine aspects of the Digital OEM and the Digital Equipment Operator are more often the norm than the exception. Nevertheless, differentiating between these two roles can be very helpful for understanding many of the different concepts associated with them.
openaire +1 more source
Low-alloy steel is widely employed in the aviation industry for its exceptional mechanical properties. These materials are frequently used in critical structural components such as aircraft landing gear and engine mounts, where a high strength-to-weight ...
Zhongyuan Che, Chong Peng
doaj +1 more source
Observer‐Based Adaptive Event‐Triggered Tracking Control for Fuzzy TS Systems With Premise Mismatch
This paper presents an adaptive logistic event‐triggered observer‐based tracking controller for Takagi‐Sugeno fuzzy systems under constrained inputs and network delays. Leveraging a hybrid LMI and Secretary Bird Optimization approach, this strategy significantly minimizes communication overhead and computational burden while ensuring optimal reference ...
Oussama Djadane +3 more
wiley +1 more source
Precise modeling of gallium nitride (GaN) high-electron mobility transistors (HEMTs) is vital for ensuring reliable and scalable RF circuit design, and efficient characterization of the device behavior.
Ahmad Khusro +2 more
doaj +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
A significant part of modern natural sciences aims to establish a model-based approach to describe the behavior of physical systems and forecast their dynamics in different scenarios.
Anton Gryzlov +2 more
doaj +1 more source

