Results 71 to 80 of about 143,062 (268)

Parallel Hybrid Modeling of Al–Mg–Si Tensile Properties Using Density-Based Weighting

Metals
A hybrid modeling framework for predicting the mechanical properties of Al-Mg-Si alloys, that blends physics-based and machine-learning models, is developed and tested.
Christian Dalheim Øien, Ole Runar Myhr, Geir Ringen   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Modeling of Piercing Based on DEFORM-3D and the Ensemble OSC-PLS-ELM Method

IEEE Access, 2018
The seamless tube, being widely used in the automobile, aviation, petroleum, chemical, building, boiler, and military industries, is called the “blood vessel of industry.”The demands for high quality seamless tubes are increasing ...
Dong Xiao, Fenghua Yang, Ba Tuan Le, Shengyong Zhang   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Integrating Machine Learning with Hybrid and Surrogate Models to Accelerate Multiscale Modeling of Acute Respiratory Infections

Viruses
Accurate, efficient, and explainable modeling of the dynamics of acute respiratory infections (ARIs) remains, in many aspects, a significant challenge.
Andrey Korzin, Maria Koshkareva, Vasiliy Leonenko   +2 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Digital Twin Approaches for Gear NVH Optimization: A Literature Review of Modeling, Data Integration, and Validation Gaps

Machines
Quiet drivetrains have become a central requirement in modern electric vehicles, where the absence of engine masking makes even subtle gear tones clearly audible.
Krisztian Horvath, Ambrus Zelei
doaj   +1 more source

Hybrid Modeling Method for a DEP Based Particle Manipulation

Sensors, 2013
In this paper, a new modeling approach for Dielectrophoresis (DEP) based particle manipulation is presented. The proposed method fulfills missing links in finite element modeling between the multiphysic simulation and the biological behavior.
Mohamad Sawan, Antoine Gagne, Mohamed Amine Miled   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Fine-Scale and Population-Weighted PM_2.5 Modeling in Melbourne: Towards Detailed Urban Exposure Mapping

ISPRS International Journal of Geo-Information
Despite concern over air pollution, fine-scale spatial and demographic disparities in exposure remain largely unquantified in Australian cities due to sparse monitoring and coarse models.
Jun Gao, Xuying Ma, Qian Chayn Sun, Wenhui Cai, Xiaoqi Wang, Yifan Wang, Zelei Tan, Danyang Li, Yuanyuan Fan, Leshu Zhang, Yixin Xu, Xueyao Liu, Yuxin Ma   +12 more
doaj   +1 more source