Results 31 to 40 of about 837,134 (277)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Volatility Modelling Using Hybrid Autoregressive Conditional Heteroskedasticity (ARCH) - Support Vector Regression (SVR) [PDF]
, 2015 High fluctuations in stock returns is one problem that is considered by the investors. Therefore we need a model that is able to predict accurately the volatility of stock returns.
Hoyyi, Abdul, Tarno, T., Yasin, Hasbi
core +3 more sources
, 2019 Representing the reservoir as a network of discrete compartments with neighbor and non-neighbor connections is a fast, yet accurate method for analyzing oil and gas reservoirs.
Castineira, David +5 more
core +1 more source
Hybrid modeling, HMM/NN architectures, and protein applications [PDF]
, 1996 We describe a hybrid modeling approach where the parameters of a model are calculated and modulated by another model, typically a neural network (NN), to avoid both overfitting and underfitting.
Baldi, Pierre, Chauvin, Yves
core +1 more source
Hybrid cognitive diagnostic model
Behaviormetrika, 2020 Cognitive diagnostic models can be classified into two categories based on the type of interaction between attributes: disjunctive and conjunctive. A representative example of the former is the “Deterministic Input Noisy-Or gate” (DINO) model, and of the latter is the “Deterministic Input Noisy-And gate” (DINA) model.
Kazuhiro Yamaguchi, Kensuke Okada
openaire +1 more source
A hybrid model of categorization [PDF]
Psychonomic Bulletin & Review, 2001 Category learning is often modeled as either an exemplar-based or a rule-based process. This paper shows that both strategies can be combined in a cognitive architecture that was developed to model other task domains. Variations on the exemplar-based random walk (EBRW) model of Nosofsky and Palmeri (1997b) and the rule-plus-exception (RULEX) rule-based
J R, Anderson, J, Betz
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Stochastic Modeling of Hybrid Cache Systems
, 2016 In recent years, there is an increasing demand of big memory systems so to perform large scale data analytics. Since DRAM memories are expensive, some researchers are suggesting to use other memory systems such as non-volatile memory (NVM) technology to ...
Chen, Jiqiang +4 more
core +1 more source
Diagnostics of an Aircraft Engine Pumping Unit Using a Hybrid Approach based-on Surrogate Modeling [PDF]
, 2013 This document introduces a hybrid approach for fault detection and identification of an aircraft engine pumping unit. It is based on the complementarity between a model-based approach accounting for uncertainties aimed at quantifying the degradation ...
LAMOUREUX, Benjamin +2 more
core +5 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source