Results 41 to 50 of about 155,289 (268)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Dynamical patterns of EEG connectivity unveil Parkinson’s disease progression: insights from machine learning analysis

Journal of Physics: Complexity
Parkinson’s disease (PD) is a multifactorial neurodegenerative disorder with complex progression. This study aims to analyze electroencephalography (EEG) connectivity patterns to better understand PD progression and stage of the disease using machine ...
Caroline L Alves, Loriz Francisco Sallum, Francisco Aparecido Rodrigues, Thaise G L de O Toutain, Patrícia Maria de Carvalho Aguiar, Michael Moeckel   +5 more
doaj   +1 more source

Linking Bayesian and agent-based models to simulate complex social-ecological systems in semi-arid regions

Frontiers in Environmental Science, 2015
Interdependencies of ecologic, hydrologic, and social systems challenge traditional approaches to natural resource management in semi-arid regions. As a complex social-ecological system, water demands in the Sonoran Desert from agricultural and urban ...
Aloah J Pope, Randy eGimblett
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

A Hybrid Methodology Using Machine Learning Techniques and Feature Engineering Applied to Time Series for Medium- and Long-Term Energy Market Price Forecasting

Energies
In the electricity market, the issue of contract negotiation prices between generators/traders and buyers is of particular relevance, as an accurate contract modeling leads to increased financial returns and business sustainability for the various ...
Flávia Pessoa Monteiro, Suzane Monteiro, Carlos Rodrigues, Josivan Reis, Ubiratan Bezerra, Maria Emília Tostes, Frederico A. F. Almeida   +6 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Enhancing Supercapacitor Simulation Accuracy Through a Novel Hybrid Modeling Approach

Applied Sciences
In the last 2 decades, supercapacitors have become an important component in the hybrid energy-storage system, in combination with batteries. The resulting system offers higher performance in comparison to classic energy storage systems due to the ...
Diana Lemian, Florin Ioan Bode, Ciprian Lapusan   +2 more
doaj   +1 more source

Physics-Informed Data-Driven Model for Predicting Streamflow: A Case Study of the Voshmgir Basin, Iran

Applied Sciences, 2022
Accurate rainfall-runoff modeling is crucial for water resource management. However, the available models require more field-measured data to produce accurate results, which has been a long-term issue in hydrological modeling.
Peiman Parisouj, Esmaiil Mokari, Hamid Mohebzadeh, Hamid Goharnejad, Changhyun Jun, Jeill Oh, Sayed M. Bateni   +6 more
doaj   +1 more source

On A nonstandard model of hybrid automaton

2010 IEEE International Conference on Control Applications, 2010
In this paper, we introduce an enlargement of a standard hybrid automaton (HA) called a nonstandard hybrid automaton (NHA) which is another model of HA in the domain of *ℝ rather than ℝ. We define two kinds of almost periodic trajectories called the z-*cycle and p-* cycle on NHA, and we discuss a slightly extended Zeno (*Zeno) and a limit cycle in ...
Nakamura, Katsunori, Fusaoka, Akira
openaire   +3 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source