Results 51 to 60 of about 7,747,162 (359)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Experimental evaluation of the seismic performance of steel MRFs with compressed elastomer dampers using large-scale real-time hybrid simulation [PDF]

open access: yes, 2011
Real-time hybrid simulation combines experimental testing and numerical simulation, and thus is a viable experimental technique for evaluating the effectiveness of supplemental damping devices for seismic hazard mitigation.
Karavasilis, Theodore L.   +11 more
core   +1 more source

Development of a Multidimensional Computerized Adaptive Test based on the Bifactor Model

open access: yesInternational Journal of Assessment Tools in Education, 2020
The purpose of this study was to conduct a real-time multidimensional computerized adaptive test (MCAT) using data from a previous paper-pencil test (PPT) regarding the grammar and vocabulary dimensions of an end-of-term proficiency exam conducted on ...
Selahattin Gelbal, Murat Doğan Şahin
doaj   +1 more source

Hybrid Simulation for Large-Scale AC/DC Power System by Serial Interaction Process

open access: yesFrontiers in Energy Research, 2021
Electromechanical transient (EMT) and transient stability hybrid simulations can make full use of their fast-solving ability and high-precision computing ability to accurately simulate the dynamic characteristics of large-scale AC/DC systems.
Song Zhang   +3 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Hybrid modelling and simulation of a computer numerical control machine tool feed drive [PDF]

open access: yes, 2004
The paper presents a new approach to the modelling and simulation of a computer numerical control (CNC) machine tool feed drive. The hybrid model of the drive incorporates a distributed load, explicit damping factors and measured non-linear effects in ...
C Pislaru   +5 more
core   +1 more source

Hybrid simulation modelling of the human-production process interface in lean manufacturing systems

open access: yesInternational Journal of Lean Six Sigma, 2019
Purpose This study aims to seek to advance a system dynamics-discrete event hybrid simulation modelling concept useful for taking improvement decisions where one needs to consider the interactions between human factors and process flow elements in lean ...
Omogbai Oleghe, K. Salonitis
semanticscholar   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

Computer simulation of a series and parallel hybrid electric vehicle [PDF]

open access: yes, 1998
Although the internal combustion engine (ICE) vehicle is the most popular vehicle type in the world it has serious problems relating to its exhaust emissions and the limitation of petroleum resource.
Lee, Wonhee
core  

Multiscale simulation of non-isothermal microchannel gas flows [PDF]

open access: yes, 2014
This paper describes the development and application of an efficient hybrid continuum-molecular approach for simulating non-isothermal, low-speed, internal rarefied gas flows, and its application to flows in Knudsen compressors.
Patronis, Alexander, Lockerby, Duncan A.
core   +1 more source

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