Results 1 to 10 of about 2,041,828 (274)

Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing

Frontiers in Cell and Developmental Biology, 2023
The control of severe or chronic pain has relied heavily on opioids and opioid abuse and addiction have recently become a major global health crisis. Therefore, it is imperative to develop new pain therapeutics which have comparable efficacy for pain ...
Siddharth Nimbalkar, Xiufang Guo, Alisha Colón, Max Jackson, Nesar Akanda, Aakash Patel, Marcella Grillo, James J. Hickman, James J. Hickman   +8 more
doaj   +1 more source

Comparative Study of the Influence of Heat Treatment and Additive Manufacturing Process (LMD & L-PBF) on the Mechanical Properties of Specimens Manufactured from 1.2709

Crystals, 2023
(1) This work answers the question of whether and to what extent there is a significant difference in mechanical properties when different additive manufacturing processes are applied to the material 1.2709.
Stefan Gnaase, Dennis Niggemeyer, Dennis Lehnert, Christian Bödger, Thomas Tröster   +4 more
doaj   +1 more source

A Vision of Collaborative Verification-Driven Engineering of Hybrid Systems [PDF]

, 2013
. Hybrid systems with both discrete and continuous dynamics are an important model for real-world physical systems. The key challenge is how to ensure their correct functioning w.r.t. safety requirements.
Mitsch, Stefan, Passmore, Grant Olney, Platzer, André   +2 more
core   +5 more sources

Hybrid Model Based on an SD Selection, CEEMDAN, and Deep Learning for Short-Term Load Forecasting of an Electric Vehicle Fleet

Applied Sciences, 2022
Forecasting the aggregate charging load of a fleet of electric vehicles (EVs) plays an important role in the energy management of the future power system.
Ahmad Mohsenimanesh, Evgueniy Entchev, Filip Bosnjak   +2 more
doaj   +1 more source

Improving the traffic situation by shifting the turn and adjusting the traffic lights [PDF]

E3S Web of Conferences, 2023
The article deals with the problem of the formation of a traffic jam on the one of the street Krasnoyarsk cities. According to statistics, the largest set of accidents occur when turning the vehicle.
Stupin Artem, Kazakovtsev Lev, Stupina Alena, Antamoshkin Oleslav, Stasiuk Vladislav   +4 more
doaj   +1 more source

A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics

Frontiers in Cell and Developmental Biology, 2021
Myasthenia gravis (MG) is a chronic and progressive neuromuscular disease where autoantibodies target essential proteins such as the nicotinic acetylcholine receptor (nAChR) at the neuromuscular junction (NMJ) causing muscle fatigue and weakness ...
Virginia M. Smith, Virginia M. Smith, Huan Nguyen, John W. Rumsey, Christopher J. Long, Michael L. Shuler, James J. Hickman, James J. Hickman   +7 more
doaj   +1 more source

Graphenic Carbon: A Novel Material to Improve the Reliability of Metal-Silicon Contacts

IEEE Journal of the Electron Devices Society, 2017
Contact resistance and thermal degradation of metal-silicon contacts are major challenges in nanoscale CMOS as well as in power device applications. Titanium silicide (TiSi) is commonly used to establish low-barrier height contacts to silicon, in state ...
Max Stelzer, Moritz Jung, Franz Kreupl
doaj   +1 more source

Novel Biocement/Honey Composites for Bone Regenerative Medicine

Journal of Functional Biomaterials, 2023
New biocements based on a powdered mixture of calcium phosphate/monetite (TTCPM) modified with the addition of honey were prepared by mixing the powder and honey liquid components at a non-cytotoxic concentration of honey (up to 10% (w/v)).
Lubomir Medvecky, Maria Giretova, Radoslava Stulajterova, Tibor Sopcak, Pavlina Jevinova, Lenka Luptakova   +5 more
doaj   +1 more source

Hybrid Geometric Reduction of Hybrid Systems [PDF]

, 2006
This paper presents a unifying framework in which to carry out the hybrid geometric reduction of hybrid systems, generalizing classical reduction to a hybrid ...
Ames, Aaron D., Sastry, Shankar
core   +1 more source

Integration of photocatalytic and dark-operating catalytic biomimetic transformations through DNA-based constitutional dynamic networks

Nature Communications, 2021
Nucleic acid-based constitutional dynamic networks (CDNs) enable control of various catalytic processes, but it is challenging to achieve intercommunication between different CDNs and by that mimic complex cell biology networks.
Chen Wang, Michael P. O’Hagan, Ehud Neumann, Rachel Nechushtai, Itamar Willner   +4 more
doaj   +1 more source