A Hybrid Optimization Algorithm for Enhancing Transportation and Logistics Scheduling in IoT-Enabled Supply Chains. [PDF]
Jihad AA +3 more
europepmc +1 more source
Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih +12 more
wiley +1 more source
A machine learning framework for predicting fuel consumption and CO2 emissions in hybrid and combustion vehicles: comparative analysis and performance evaluation. [PDF]
Ibrahim RA, Zakzouk NE.
europepmc +1 more source
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen +16 more
wiley +1 more source
Real-world evaluat ion of hybrid Green AI for sustainable and efficient smart supply chain distribution. [PDF]
Hassouna MA +3 more
europepmc +1 more source
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang +8 more
wiley +1 more source
Vehicle Aerodynamic Noise: A Systematic Review of Mechanisms, Simulation Methods, and Bio-Inspired Mitigation Strategies. [PDF]
Zou T, Fu Y, Cao P.
europepmc +1 more source
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong +12 more
wiley +1 more source
Steady-State Characteristic Assessment and Dynamic Performance Testing for a Metal-Supported Solid Oxide Fuel Cell Auxiliary Power Unit with Methanol On-Board Reforming. [PDF]
Ma S, Xue K, Jia R, Ren X, Zhao H, Li Y.
europepmc +1 more source

