Results 61 to 70 of about 3,369,459 (368)

SIMILARITIES AND DIFFERENCES BETWEEN THE ARMED CONFRONTATIONS IN THE MIDDLE EAST AND UKRAINE [PDF]

open access: yesJournal of Defense Resources Management, 2015
The current paper highlights the possibilities of methodologically working with the concept of hybrid warfare within an international environment characterized by high marginal conflicts.
Daniel STEFANESCU
doaj  

Power, Politics, and Domestic Desire in Octavia Butler’s Lilith’s Brood [PDF]

open access: yes, 2013
Octavia Butler’s works, from her short stories and novellas to her science fiction novels, focus on themes of power, control, bondage, and a desired freedom from servitude.
Nanda, Aparajita
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Introduction: Targeting in an Asymmetrical World [PDF]

open access: yes, 2012
This is the introduction to a collection of articles to be published in the Valparaiso University Law Review. The articles address the challenges presented by non-traditional warfare and non-traditional combatants in the contexts of the War on Terror and
Telman, D. A. Jeremy
core   +3 more sources

Re-colonizing spaces of memorializing: the case of the Chattri Indian Memorial, UK [PDF]

open access: yes, 2016
This article inspects the ways that spaces of war memorialization are organized and reorganized through official and unofficial meaning-making activities. It aims to contribute to the discussion of the ‘value’ of memorializing by examining a multifaceted
Alan Cresswell (1686997)   +8 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Hybrid War Threats and Essence of Perception Management: Challenges for Pakistan

open access: yesIPRI Journal, 2020
The Combat in the twenty first century is not only influenced by unprecedented technological and technical innovations but also characterized with progressive evolution of the art of warfighting.
A. Abbasi
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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