Sensitivity, Specificity and the Hybridization Isotherms of DNA Chips [PDF]
Competitve hybridization, at the surface and in the bulk, lowers the sensitivity of DNA chips. Competitive surface hybridization occurs when different targets can hybridize with the same probe.
A. Buhot+40 more
core +3 more sources
Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84 [PDF]
The localization of chromosome 18 in human interphase nuclei is demonstrated by use of radioactive and nonradioactive in situ hybridization techniques with a DNA clone designated L1.84.
A. Brückner+33 more
core +1 more source
Modeling the kinetics of hybridization in microarrays [PDF]
Conventional fluorescent-based microarrays acquire data after the hybridization phase. In this phase the targets analytes (i.e., DNA fragments) bind to the capturing probes on the array and supposedly reach a steady state.
Hassibi, A.+3 more
core +1 more source
Green function theory of dirty two-band superconductivity [PDF]
We study the effects of random nonmagnetic impurities on the superconducting transition temperature $T_c$ in a two-band superconductor, where we assume the equal-time spin-singlet s-wave pair potential in each conduction band and the hybridization ...
Asano, Yasuhiro, Golubov, Alexander A.
core +9 more sources
The challenge of hybridization [PDF]
Hybridization of pixel detector systems has to satisfy tight requirements: high yield, long term reliability, mechanical stability, thermal compliance and robustness have to go together with low passive mass added to the system, radiation hardness ...
Becks+12 more
core +3 more sources
Multiple ITS Copies Reveal Extensive Hybridization within Rheum (Polygonaceae), a Genus That Has Undergone Rapid Radiation [PDF]
During adaptive radiation events, characters can arise multiple times due to parallel evolution, but transfer of traits through hybridization provides an alternative explanation for the same character appearing in apparently non-sister lineages.
A Gelman+105 more
core +3 more sources
In contrast to previous efforts to model an individual's movement from wage work into entrepreneurship, we consider that individuals might transition incrementally by retaining their wage job while entering into self-employment. We show that these hybrid entrepreneurs represent a significant share of all entrepreneurial activity.
Folta, Timothy B.+2 more
openaire +4 more sources
In vitro identification and in silico utilization of interspecies sequence similarities using GeneChip(® )technology [PDF]
BACKGROUND: Genomic approaches in large animal models (canine, ovine etc) are challenging due to insufficient genomic information for these species and the lack of availability of corresponding microarray platforms. To address this problem, we speculated
Garcia, Joe GN+5 more
core +3 more sources
A Hybrid Model for a Hybrid Science [PDF]
This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies
openaire +4 more sources
Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries [PDF]
A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported.
B Trask+39 more
core +1 more source