Results 61 to 70 of about 22,641 (251)
Mode of Action of Isonicotinic Hydrazide [PDF]
Nature, 1956 IN our earlier report we directed attention to the importance of chelation as an essential step in the anti-tuberculous activity of isonicotinic hydrazide (isoniazid)1. It was impossible to decide whether the chelating action with a metal or metals took place before (in the medium) or after adsorption on the bacterial cell.
S D, RUBBO +4 more
openaire +2 more sources
THE ESTIMATION OF MALEIC HYDRAZIDE BY PAPER CHROMATOGRAPHY
, 1958 Maleic hydrazide added to solutions of partially purified plant extracts can be determined semiquantitatively by a paper chromatographic method in which the area of the maleic hydrazide spot, detected by spraying with a mixture of ferric chloride and ...
W. A. Andreae
core +1 more source
Microwave-Assisted Synthesis and Biological Evaluation of Some Coumarin Hydrazides
Journal of the Turkish Chemical Society, Section A: Chemistry, 2018 In this work, 15 different coumarin hydrazides were successfully synthesized and screened for their antioxidant and antilipase activities. To do this, firstly, salicylaldehyde derivatives and 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum's Acid) were ...
Fatih Yılmaz, Özlem Faiz
doaj +1 more source
Mechanochemical Amidation Mediated by 1,1’‐Oxalyldiimidazole for the Synthesis of Agrochemicals
Chemistry – A European Journal, EarlyView.Mechanochemical amidation using 1,1'‐oxalyldiimidazole (ODI) overcomes limitations of 1,1’‐carbonyl diimidazole (CDI) as coupling agent by enabling the efficient mechanochemical synthesis of three marketed agrochemicals from deactivated carboxylic acids.
Andrea Casagrande +6 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu +6 more
wiley +1 more source
Solid Phase Extraction of N‑Linked Glycopeptides Using Hydrazide Tip
, 2016 Glycoproteome contains valuable information where biomarkers may be discovered for disease diagnosis and monitoring. Nowadays, with the ever-increasing performances of mass spectrometers, the emphasis is shifting to the sample preparation for better ...
Punit Shah (1326501) +2 more
core +2 more sources
Preparation and determining of a number of elemental complexes with hydrazone ligand derived from ibuprofen [PDF]
مجلة جامعة الانبار للعلوم الصرفةThis study addresses the synthesis and characterization of seven new complexes of a hydrazone ligand derived from a non-steroidal anti-inflammatory drug (ibuprofen) via condensation with p-nitroacetophenone, followed by reaction with cobalt(II), nickel ...
Fayhaa Al-garah, Sahbaa Ahmed
doaj +1 more source
Drug Testing and Analysis, EarlyView.An ultrasensitive LC‐MS/MS method for detecting testosterone esters (T‐esters) in urine at sub–pg/mL levels is presented. This approach, employing Girard P derivatization, provides the first evidence of T‐esters' trace‐level detectability in human urine.
Daniel Pecher +3 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane +4 more
wiley +1 more source
First mixed hydrazide/hydroxylamide metal aggregates
, 2006 Jana S, Berger R, Fröhlich R, Mitzel NW. First mixed hydrazide/hydroxylamide metal aggregates. CHEMICAL COMMUNICATIONS. 2006;(38):3993-3995.The first organometallic clusters of mixed hydrazide/hydroxylamide clusters of zinc, [Zn(MeZn)(4)(HNNMe2)(2)(ONEt2)
Fröhlich, Roland +3 more
core +1 more source