Results 21 to 30 of about 2,042 (119)

Synthesis, Characterization, Theoretical Treatment and Antitubercular activity Evaluation of (E)-N’- (2,5-dimethoxylbenzylidene)nicotinohydrazide and some of its Transition Metal Complexes against Mycobacterium tuberculosis, H37Rv [PDF]

, 2016
(E)-N’-(2,5-dimethoxylbenzylidene)nicotinohydrazide) (HL) was synthesized by condensing nicotinic acid hydrazide and 2,5-dimethoxylbenzaldehyde with ONO coordination pattern.
Adekoya, J. A.
core   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Volume 64, Issue 41, October 6, 2025.
This review highlights mechanochemical strategies for the late‐stage modification of active pharmaceutical ingredients (APIs), providing a valuable resource for selecting substrates to evaluate the pharmaceutical potential of novel and existing (mechano)chemical protocols.
Johanna Templ, Lars Borchardt
wiley   +1 more source

Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides [PDF]

, 2014
A series of phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides (TTa-TTg) were synthesized by the ring closure reaction of phenyl-1-(thiophen-2-yl) prop-2-en-1-ones with thiosemicarbazide in alcoholic basic medium.
Anbazhagan, S., Mathew, Bijo, Suresh, Jerad   +2 more
core  

Inhibitory effect of Clitoria ternatea flower petal extract on fructose-induced protein glycation and oxidation-dependent damages to albumin in vitro [PDF]

, 2015
Background: The accumulation of advanced glycation end products (AGEs) in body tissue has been implicated in the progression of age-related diseases. Inhibition of AGE formation is the imperative approach for alleviating diabetic complications.
Adisakwattana, Sirichai, Barbieri, Manuel Alejandro, Chayaratanasin, Poramin, Suanpairintr, Nipattra   +3 more
core   +1 more source

The Bioactive Potential of Fruit Juice of Black Chokeberry (Aronia melanocarpa) Produced in Edirne Province‐Türkiye: Phenolic Profile, Elemental Composition, and In Vitro Antioxidant and Antibacterial Activities

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
The study investigates the bioactive properties of Aronia melanocarpa (black chokeberry) juice produced in Edirne, Türkiye. It found that the juice is rich in phenolic acids and flavonoids, showing significant antioxidant and antibacterial activity, especially against Gram‐positive bacteria.
Fatmagul Halici Demir, Gokhan Acik, Duygu Sahin Gul   +2 more
wiley   +1 more source

Serotonin (5‐Hydroxytryptamine): Metabolism, Signaling, Biological Functions, Diseases, and Emerging Therapeutic Opportunities

MedComm, Volume 6, Issue 9, September 2025.
This article reviews the roles of 5‐HT metabolism, 5‐HT receptors, and their related signaling pathways in normal physiology and various diseases, and explores their potential value in disease treatment, providing a reference basis for research and clinical treatment in related fields. ABSTRACT Serotonin (5‐hydroxytryptamine; 5‐HT) is an evolutionarily
Yuxin Zhang, Nan Wang, Louqian Zhang, Yan Zhuang, Qilei Xin, Xiaosong Gu, Chunping Jiang, Junhua Wu   +7 more
wiley   +1 more source

An Approach towards the synthesis of furo[3,4-c]pyrazole [PDF]

, 2009
Synthesis of pyrazole and its N-aryl analogues has been a subject of consistent interest because of the wide applications of such heterocycles in pharmaceutical as well as in agrochemical industry.
Sahoo, Krushna Chandra
core  

Monoaminergic and histaminergic strategies and treatments in brain diseases [PDF]

, 2016
The monoaminergic systems are the target of several drugs for the treatment of mood, motor and cognitive disorders as well as neurological conditions.
Adell, Ahles, Ahmed, Airas, Aletrino, Alper, Andersson, Anna Stasiak, Arai, Arrang, Artigas, Artigas, Artigas, Artigas, Ashby, Ban, Bar-Am, Barak, Barak, Barnes, Bastide, Bauer, Bautista-Aguilera, Beaulieu, Bel, Benarroch, Berman, Bett, Bezard, Bezard, Bezard, Bhide, Bialer, Binda, Blier, Blier, Boomsma, Braak, Bronstein, Brown, Buckley, Bunney, Burke, Butini, Bézard, Carboni, Cardamone, Carlsson, Carruba, Carta, Chang, Cipriani, Cirrito, Citrome, Citrome, Claeysen, Clineschmidt, Combarros, Conklin, Cooper, Cotzias, Cotzias, Coulter, Cremers, Cremers, Cryan, Cryan, Curet, Dale, Davidson, Daws, De Deurwaerdère, De Deurwaerdère, De Deurwaerdère, De Deurwaerdère, De Deurwaerdère, de la Fuente-Fernández, de la Fuente-Fernández, del Mar Hernandez, Del Tredici, Delaville, Delaville, Delgado, Deroche-Gamonet, Deutch, Devinsky, Devroye, Di Chiara, Di Chiara, Di Chiara, Di Giovanni, Di Giovanni, Dias, DiNapoli, Dorotea Mück-Šeler, Dubravka Svob Strac, Durif, Ebadi, Eisenhofer, Elrod, Emilien, Esbenshade, Fakhfouri, Fakhfouri, Fangmann, Ferrer, Fidalgo, Filip, Finberg, Fisher, Fitoussi, Fitzgerald, Fletcher, Fornito, Fowler, Fox, Friedman, Gagnon, Galati, Garattini, Garcia-Alloza, Garcia-Alloza, Gardier, Gbahou, Geldenhuys, Ghanemi, Giuseppe Di Giovanni, Grammas, Greendyke, Grudzien, Guglielmotto, Guiard, Guidi, Gumnick, Gururajan, Gustafson, Haefely, Hale, Hamon, Han, Harden, Haslam, Hauser, Hawirko, Heneka, Heneka, Hensler, Hernandez-Guillamon, Hernandez-Guillamon, Higgins, Himeno, Hiranita, Holm, Howell, Hoyer, Iadecola, Iadecola, Iderberg, Ilse J. Smolders, Invernizzi, Invernizzi, Irene Bolea, Ittner, Iversen, Jackson, Jacquot, Jalkanen, James, Jellinger, Jenner, Jobe, Joyce, Kalaria, Kalinin, Kapur, Kapur, Karran, Kasper, Keith F. Tipton, Kepe, Kiloh, Kiss, Koch, Koob, Koob, Koob, Koob, Kroeze, Kuczenski, Kumar, Kurkijärvi, Lai, Lai, Lanari, Laura Della Corte, Le Moal, Lecklin, Lees, Leggio, Leiser, León, Li, Liu, Liu, Liu, Lopez, Lorke, Lucas, Lucas, Luque, Luscombe, López-Muñoz, López-Muñoz, Marchesi, Markham, Marner, Martorana, Martorana, Masaki, Matea Nikolac Perkovic, Mateo, Mauri, Mazzucchi, McCann, McCreary, McDonald, Melamed, Meltzer, Meltzer, Meltzer, Meltzer, Meltzer, Meltzer, Meltzer, Meltzer, Meltzer, Mendez-David, Meneses, Mercedes Unzeta, Miguelez, Miguelez, Millan, Millan, Millan, Millan, Millan, Millan, Millan, Millan, Montse Sole, Morisset, Muck-Seler, Murphy, Mustapic, Myöhänen, Nakazato, Navailles, Navailles, Navailles, Navailles, Navailles, Navailles, Navailles, Nela Pivac, Olanow, Owen, Page, Palmieri, Panula, Parsons, Pascual, Payton, Perez-Caballero, Perez-Lloret, Peskind, Philippe De Deurwaerdère, Piñeyro, Porras, Poyurovsky, Preda, Provensi, Provensi, Racagni, Ramirez, Ramsay, Rantamaki, Rascol, Ratliff, Reifler, Remington, Reynolds, Rezvani, Richtand, Riederer, Ries, Rommelfanger, Rosenzweig-Lipson, Roth, Sachdev, Sagud, San, Sanchez, Sanz, Sanz, Saura, Saura, Scheen, Schendzielorz, Schreiber, Seeman, Seeman, Seeman, Shankle, Shen, Simoni, Sims, Smith, Solé, Solé, Stahl, Stansley, Stansley, Storga, Strac, Sun, Svenningsson, Szot, Tammimäki, Tanaka, Taylor, Terry, Thase, Thomas, Tighilet, Tohgi, Tonelli, Torres, Trillo, Tronci, Udenfriend, Versijpt, Vickers, Visanji, Vivero, Voigt, Werner, Wieslawa A. Fogel, Wimalasena, Wong, Yan, Youdim, Yu, Zeller, Zlokovic, Zohar, Šimić   +355 more
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SiO2@Benzothiazole‐Cl@Fc as an Efficient Heterogeneous Catalyst for the Synthesis of 1,3,5‐Trisubstituted Pyrazoles by A3 Coupling

ChemistryOpen, Volume 14, Issue 8, August 2025.
This research introduces the preparation and analysis of a newly heterogeneous catalyst developed silica nanospheres supporting a ferrocene‐containing ionic liquid (SiO2@Benzothiazole‐Cl@Fc) for the A3 coupling reaction. The catalyst facilitates the efficient synthesis of 1,3,5‐trisubstituted pyrazoles from aromatic hydrazides, aldehydes, and aromatic ...
Fadhil Faez Sead, Vicky Jain, Roopashree R, Aditya Kashyap, Suman Saini, Girish Chandra Sharma, Pushpa Negi Bhakuni, Mosstafa Kazemi, Ramin Javahershenas   +8 more
wiley   +1 more source

Moving to the Beat of Djembe Drums: African Dance and Reported Feelings of Depression [PDF]

, 2010
Depression is a disabling mental disorder that has huge impacts on one’s life and is therefore considered a global health concern. Efforts to find the most effective treatments have led to the development of antidepressants and cognitive therapy ...
Anderson, Jacquilyn D.
core   +2 more sources