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Metabolic bioactivation of antidepressants: advance and underlying hepatotoxicity. [PDF]
Drug Metab RevKhalil SM +3 more
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Psychopharmacology, 1979
Microsome-free preparations of rodent and human liver were shown to contain N-acetyl transferase from experiments using procainamide as substrate. These preparations then acetylated phenelzine from the quantitative transfer of radiolabeled acetate. This in vitro demonstration of phenelzine acetylation in rodent and human liver was corroborated by the ...
W J, Tilstone, P, Margot, E C, Johnstone
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Microsome-free preparations of rodent and human liver were shown to contain N-acetyl transferase from experiments using procainamide as substrate. These preparations then acetylated phenelzine from the quantitative transfer of radiolabeled acetate. This in vitro demonstration of phenelzine acetylation in rodent and human liver was corroborated by the ...
W J, Tilstone, P, Margot, E C, Johnstone
openaire +2 more sources