Results 31 to 40 of about 2,947 (138)
Frontiers in Neuroscience, 2020 Besides several endogenous elements, exogenous factors, including exposure to pesticides, have been recognized as putative factors contributing to the onset and development of neurodegenerative diseases, including Parkinson’s disease (PD).
Thomson Patrick Joseph +7 more
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Acta Pharmaceutica, 2017 γ-Ethyl-γ-phenyl-butyrolactone (EFBL) is a structural combination of the anticonvulsant γ-hydroxy-γ-ethyl-γ-phenylbutyramide (HEPB) and the hypnotic γ-butyrolactone (GBL), which inherits both properties. To clarify its mechanism of action, the effects of
Rasgado Lourdes A. Vega +2 more
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Clinical Pharmacology: Advances and Applications, 2020 Hinz M, Stein A, Cole T, Ryan P. Clin Pharmacol Adv Appl. 2014;6:107– 110. The Editor-in-Chief and Publisher of Clinical Pharmacology: Advances and Applications wish to issue an Expression of Concern for the published article ...
Hinz M, Stein A, Cole T, Ryan P
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Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). [PDF]
PLoS Pathogens, 2011 The essential transactivator function of the HIV Tat protein is regulated by multiple posttranslational modifications. Although individual modifications are well characterized, their crosstalk and dynamics of occurrence during the HIV transcription cycle
Naoki Sakane +10 more
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Administration of supplemental L-tyrosine with phenelzine: a clinical literature review
Clinical Pharmacology: Advances and Applications, 2014 Marty Hinz,1 Alvin Stein,2 Ted Cole,3 Patricia Ryan4 1Clinical Research, NeuroResearch Clinics, Inc., Cape Coral, FL, USA; 2Stein Orthopedic Associates, Plantation, FL, USA; 3Cole Center for Healing, Cincinnati, OH, USA; 4Family Wellness Center, Omaha ...
Hinz M, Stein A, Cole T, Ryan P
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Phenelzine: An old drug that may hold clues to the development of new neuroprotective agents
Psychiatry and Clinical Psychopharmacology, 2021 The monoamine oxidase (MAO)-inhibiting antidepressant phenelzine (PLZ) is also used in the treatment of anxiety disorders such as panic disorder and social anxiety disorder and has been shown to have neuroprotective actions in an animal model of ...
Erin M. MacKenzie +5 more
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REVERSİBLE MAO İNHİBİTORS İN THE TREATMENT OF PANİC DISORDERS
Psychiatry and Clinical Psychopharmacology, 2021 Members of three classes of drugs have been shown to have efficacy-tricyclic antidepressants,monoamine oxidase inhibitors and benzodiazepins. Imipramine and clomipramine have been the tricyclic antidepressants most extensively studied.
Nesrin DİLBAZ +3 more
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Journal of Pharmacy & Pharmaceutical Sciences, 2008 PURPOSE. To compare phenelzine (PLZ), an antidepressant drug with anxiolytic properties which inhibits monoamine oxidase (MAO) but also elevates rat brain levels of the amino acids ?-aminobutyric acid (GABA) and alanine (ALA), with vigabatrin (VIG ...
Kathryn G. Todd, Glen B. Baker
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BMC Neuroscience, 2010 Background The molecular and biological mechanisms by which many antidepressants function are based on the monoamine depletion hypothesis. However, the entire cascade of mechanisms responsible for the therapeutic effect of antidepressants has not yet ...
Shin Minkyu +8 more
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MoleculesLysine-specific demethylase 1 (LSD1/KDM1A) has emerged as a promising therapeutic target for treating various cancers (such as breast cancer, liver cancer, etc.) and other diseases (blood diseases, cardiovascular diseases, etc.), owing to its observed ...
Di Han +10 more
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