Results 31 to 40 of about 2,974 (154)
Pharmaceuticals, 2020 Treatment with several antipsychotic drugs exhibits a tendency to induce weight gain and diabetic complications. The proposed mechanisms by which the atypical antipsychotic drug olanzapine increases body weight include central dysregulations leading to ...
Christian Carpéné +8 more
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Frontiers in Genetics, 2021 Variability in the enzymatic activity of N-acetyltransferase 2 (NAT2) is an important contributor to interindividual differences in drug responses. However, there is little information on functional differences in N-acetylation activities according to ...
Koya Fukunaga +8 more
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LSD1 inhibitors for cancer treatment: Focus on multi-target agents and compounds in clinical trials
Frontiers in Pharmacology, 2023 Histone lysine-specific demethylase 1 (LSD1/KDM1A) was first identified in 2004 as an epigenetic enzyme able to demethylate specific lysine residues of histone H3, namely H3K4me1/2 and H3K9me1/2, using FAD as the cofactor.
Beatrice Noce +4 more
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A Case of the Serotonin Syndrome Secondary to Phenelzine Monotherapy at Therapeutic Dosing
Case Reports in Medicine, 2015 A 27-year-old Caucasian female with a history of depression was admitted to our local hospital with vague events that occurred a day before. This included an episode of dysarthria, and unsteadiness, followed by feeling generally unwell.
A. Malik, N. Junglee
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Nature Communications, 2020 Castration resistant prostate cancer patients treated with enzalutamide may develop resistance to the drug. Here, the authors report that monoamine oxidase-A expression is increased in these resistant tumors and that the antidepressants phenelzine ...
Keliang Wang +14 more
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BMC Psychiatry, 2020 Background Antidepressants-induced movement disorders are rare and imperfectly known adverse drug reactions. The risk may differ between different antidepressants and antidepressants’ classes.
Alexis Revet +5 more
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Effects of Different Psychotropic Agents on the Central Nerve Growth [PDF]
Iranian Journal of Basic Medical Sciences, 2010 Psychotropic medications produce their effects, in part, through increasing neurotrophin levels in the brain. Since studies concerning nerve growth factor (NGF) analysis have been limited in scope, in the current experiments we investigated the effects ...
Parichehr Hassanzadeh, Anna Hassanzadeh
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Medicines, 2019 Background: Two classes of amine oxidases are found in mammals: those with a flavin adenine dinucleotide as a cofactor, such as monoamine oxidases (MAO) and lysine-specific demethylases (LSD), and those with copper as a cofactor, including copper ...
Christian Carpéné +3 more
doaj +1 more source
Administration of Supplemental L-Tyrosine with Phenelzine: a Clinical Literature Review [Retraction]
Clinical Pharmacology: Advances and Applications, 2021 Hinz M, Stein A, Cole T, Ryan P. Clin Pharmacol. 2014;6:107–110.The Editor-in-chief and Publisher of Clinical Pharmacology: Advances and Applications wish to retract the published article.This review article cites several original ...
Hinz M, Stein A, Cole T, Ryan P
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European Psychiatry, 2021 Introduction Serotonin syndrome (SS) is a toxic state characterized by increased serotonin activity. It has been suggested that severe serotonin syndrome usually involves monoaminoxidase inhibitors (MAOIs). Objectives To quantify in how far severe SS
P. Truedson +5 more
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