Results 21 to 30 of about 2,947 (138)

A Case of the Serotonin Syndrome Secondary to Phenelzine Monotherapy at Therapeutic Dosing

open access: yesCase Reports in Medicine, 2015
A 27-year-old Caucasian female with a history of depression was admitted to our local hospital with vague events that occurred a day before. This included an episode of dysarthria, and unsteadiness, followed by feeling generally unwell.
A. Malik, N. Junglee
doaj   +1 more source

The MAO inhibitors phenelzine and clorgyline revert enzalutamide resistance in castration resistant prostate cancer

open access: yesNature Communications, 2020
Castration resistant prostate cancer patients treated with enzalutamide may develop resistance to the drug. Here, the authors report that monoamine oxidase-A expression is increased in these resistant tumors and that the antidepressants phenelzine ...
Keliang Wang   +14 more
doaj   +1 more source

Antidepressants and movement disorders: a postmarketing study in the world pharmacovigilance database

open access: yesBMC Psychiatry, 2020
Background Antidepressants-induced movement disorders are rare and imperfectly known adverse drug reactions. The risk may differ between different antidepressants and antidepressants’ classes.
Alexis Revet   +5 more
doaj   +1 more source

Effects of Different Psychotropic Agents on the Central Nerve Growth [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2010
Psychotropic medications produce their effects, in part, through increasing neurotrophin levels in the brain. Since studies concerning nerve growth factor (NGF) analysis have been limited in scope, in the current experiments we investigated the effects ...
Parichehr Hassanzadeh, Anna Hassanzadeh
doaj  

Past, Present and Future Anti-Obesity Effects of Flavin-Containing and/or Copper-Containing Amine Oxidase Inhibitors

open access: yesMedicines, 2019
Background: Two classes of amine oxidases are found in mammals: those with a flavin adenine dinucleotide as a cofactor, such as monoamine oxidases (MAO) and lysine-specific demethylases (LSD), and those with copper as a cofactor, including copper ...
Christian Carpéné   +3 more
doaj   +1 more source

Administration of Supplemental L-Tyrosine with Phenelzine: a Clinical Literature Review [Retraction]

open access: yesClinical Pharmacology: Advances and Applications, 2021
Hinz M, Stein A, Cole T, Ryan P. Clin Pharmacol. 2014;6:107–110.The Editor-in-chief and Publisher of Clinical Pharmacology: Advances and Applications wish to retract the published article.This review article cites several original ...
Hinz M, Stein A, Cole T, Ryan P
doaj  

Monoaminoxidase inhibitors as a cause of serotonin syndrome – a systematic case review based on meta-analytic principles

open access: yesEuropean Psychiatry, 2021
Introduction Serotonin syndrome (SS) is a toxic state characterized by increased serotonin activity. It has been suggested that severe serotonin syndrome usually involves monoaminoxidase inhibitors (MAOIs). Objectives To quantify in how far severe SS
P. Truedson   +5 more
doaj   +1 more source

Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro

open access: yesFrontiers in Pharmacology, 2022
Repurposing of currently available drugs is a valuable strategy to tackle the consequences of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on SARS-CoV-2 in cell culture models as well as in clinical practice. Our
Senem Merve Fred   +9 more
doaj   +1 more source

The Cost Effectiveness of Psychological and Pharmacological Interventions for Social Anxiety Disorder: A Model-Based Economic Analysis.

open access: yesPLoS ONE, 2015
BackgroundSocial anxiety disorder is one of the most persistent and common anxiety disorders. Individually delivered psychological therapies are the most effective treatment options for adults with social anxiety disorder, but they are associated with ...
Ifigeneia Mavranezouli   +6 more
doaj   +1 more source

Biological Evaluation, DFT Calculations and Molecular Docking Studies on the Antidepressant and Cytotoxicity Activities of Cycas pectinata Buch.-Ham. Compounds

open access: yesPharmaceuticals, 2020
Cycas pectinata Buch.-Ham. is commonly used in folk medicine against various disorders. The present study investigated the antidepressant and cytotoxicity activity of methanol extract of C.
Jinnat Rahman   +12 more
doaj   +1 more source

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