Results 1 to 10 of about 25,397 (119)

Gut microbial tyramine facilitates intestinal damage and metabolic dysfunction-associated steatotic liver disease development [PDF]

BMC Medicine
Background Emerging evidence indicates that gut microbiota and intestinal injury are crucial in pediatric metabolic dysfunction-associated steatotic liver disease (MASLD), yet the role of key gut microbial metabolites such as tyramine in pediatric MASLD ...
Jia Wei, Shuangquan Liu, Jiayou Luo, Fei Yang, Wen Dai, Zhihang Huang, Xiongfeng Pan, Miyang Luo   +7 more
doaj   +2 more sources

Rethinking, reducing, and refining the classical oral tyramine challenge test of monoamine oxidase (MAO) inhibitors

Clinical and Translational Science, 2023
The oral tyramine challenge evaluates the safety of novel monoamine oxidase (MAO) inhibitors when taken with tyramine‐containing food or drinks. In its current design, it comprises an extensive series of tyramine escalation steps until a blood pressure ...
Ewoud‐Jan vanHoogdalem, Karen L. Smith, Jan Hartstra, John Constant   +3 more
doaj   +1 more source

Tyramine and Amyloid Beta 42: A Toxic Synergy

Biomedicines, 2020
Implicated in various diseases including Parkinson’s disease, Huntington’s disease, migraines, schizophrenia and increased blood pressure, tyramine plays a crucial role as a neurotransmitter in the synaptic cleft by reducing serotonergic and dopaminergic
Sudip Dhakal, Ian Macreadie
doaj   +1 more source

The Role of Enterococcus faecium as a Key Producer and Fermentation Condition as an Influencing Factor in Tyramine Accumulation in Cheonggukjang

Foods, 2020
The study evaluated the role of Enterococcus faecium in tyramine production and its response to fermentation temperature in a traditional Korean fermented soybean paste, Cheonggukjang.
Young Kyoung Park, Young Hun Jin, Jun-Hee Lee, Bo Young Byun, Junsu Lee, KwangCheol Casey Jeong, Jae-Hyung Mah   +6 more
doaj   +1 more source

Opposing Actions of Octopamine and Tyramine on Honeybee Vision

Biomolecules, 2021
The biogenic amines octopamine and tyramine are important neurotransmitters in insects and other protostomes. They play a pivotal role in the sensory responses, learning and memory and social organisation of honeybees.
Felix Schilcher, Markus Thamm, Martin Strube-Bloss, Ricarda Scheiner   +3 more
doaj   +1 more source

In silico investigation on interaction of small Ag6 nano-particle cluster with tyramine neurotransmitter

Scientific Reports, 2023
The interaction of tyramine neurotransmitter with silver nano-particle (Ag6) cluster is explored in terms of the molecular structure, electronic properties and NBO analysis of tyramine-AgNPs bio-molecular conjugate.
Subhendu Chakroborty, E. Shakerzadeh, T. Yadav, Nilima Priyadarsini Mishra, Arundhati Barik, Versha Upadhyay, Abhilasha, Siba Soren, Jitendra Malviya, Amiya Ranjan Panda, Kartik Uniyal, Narendra Kumar, Shradha Wagadre, F. P. Pandey   +13 more
doaj   +1 more source

Effects of Sodium Chloride on Tyramine Production in a Fermented Food Model and its Inhibition by Tyrosine-degrading Lactobacillus plantarum JA-1199

CHIMIA, 2020
Tyramine is a health-adverse biogenic amine, which can accumulate in fermented foods like cheese by decarboxylation of the free amino acid tyrosine by either starter cultures or resident microbes such as lactic acid bacteria including Enterococcus spp ...
Janine Anderegg, Florentin Constancias, Leo Meile   +2 more
doaj   +1 more source

Evolution of ideas about the risk of tyramine syndrome developing during therapy with irreversible non-selective monoamine oxidase inhibitors (to the 70th anniversary of the first use of this group of antidepressants)

Неврология, нейропсихиатрия, психосоматика, 2022
We describe the history of studying of the problem of tyramine syndrome during the treatment with antidepressants, irreversible non-selective monoamine oxidase inhibitors. Data on clinical observations are presented.
D. S. Danilov, M. Yu. Brovko
doaj   +1 more source

Differences in α1-Adrenoceptor Subtype-Mediated Vasoconstriction by Tyramine and Nerve Stimulation in Canine Splenic Artery

Journal of Pharmacological Sciences, 2005
This study was designed to clarify the α1-adrenoceptor subtypes mediating the vasoconstrictor response to tyramine in isolated and perfused canine splenic artery.
Xiao-Ping Yang, Shigetoshi Chiba
doaj   +1 more source

Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A

Frontiers in Pharmacology, 2019
Tyramine, formed by the decarboxylation of tyrosine, is a natural constituent of numerous food products. As an indirect sympathomimetic, it can have potentially dangerous hypertensive effects. In vitro data indicated that the pharmacokinetics of tyramine
Muhammad Rafehi, Frank Faltraco, Johannes Matthaei, Thomas Prukop, Ole Jensen, Aileen Grytzmann, Felix G. Blome, Ralf Günter Berger, Ulrich Krings, Stefan V. Vormfelde, Mladen V. Tzvetkov, Jürgen Brockmöller   +11 more
doaj   +1 more source