Results 51 to 60 of about 2,974 (154)
Maternal &Child Nutrition, EarlyView.Maternal brewer's yeast supplementation did not change the milk oligosaccharide (HMO) concentration, but more mothers felt their milk supply was increased, and fewer reported formula use by 6 months postpartum compared to those taking the placebo. This suggests the supplement may support breastfeeding, warranting further investigation in larger trials.
Lili Jia, Louise Brough, Janet L. Weber
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From Fragments to Function: Novel Hydrazone Derivatives as Monoamine Oxidase Inhibitors
ChemMedChem, Volume 21, Issue 16, 27 August 2026.Twelve N‐acylhydrazone derivatives (5a–f, 6a–f) were synthesized and characterized. Compounds displayed potent submicromolar inhibition against both MAO‐A and MAO‐B. Compound 6e exhibited the strongest activity (IC50 = 0.073 μM for MAO‐A; 0.064 μM for MAO‐B). Kinetic and docking analyses confirmed reversible, competitive inhibition via FAD interaction.
Hasan Erdinç Sellitepe +5 more
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Administration of supplemental L-tyrosine with phenelzine: a clinical literature review
Clinical Pharmacology: Advances and Applications, 2014 Marty Hinz,1 Alvin Stein,2 Ted Cole,3 Patricia Ryan4 1Clinical Research, NeuroResearch Clinics, Inc., Cape Coral, FL, USA; 2Stein Orthopedic Associates, Plantation, FL, USA; 3Cole Center for Healing, Cincinnati, OH, USA; 4Family Wellness Center, Omaha ...
Hinz M, Stein A, Cole T, Ryan P
doaj
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background and Aims Sexual function is considered an essential criterion for enhancing the quality of life, encompassing not only the genital component but also mental and physical factors. The present study was conducted to determine the relationship between sexual attitude and sexual function among Iranian women and men during pregnancy ...
Sepideh Mashayekh‐Amiri +3 more
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Phenelzine: An old drug that may hold clues to the development of new neuroprotective agents
Psychiatry and Clinical Psychopharmacology, 2021 The monoamine oxidase (MAO)-inhibiting antidepressant phenelzine (PLZ) is also used in the treatment of anxiety disorders such as panic disorder and social anxiety disorder and has been shown to have neuroprotective actions in an animal model of ...
Erin M. MacKenzie +5 more
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Psychedelics, entactogens and psychoplastogens for depression and related disorders
British Journal of Pharmacology, Volume 183, Issue 14, Page 3897-3919, July 2026.Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
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CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.Viloxazine, a serotonin–norepinephrine modulating agent, has been repurposed from an antidepressant to a novel non‐stimulant for ADHD. Its multimodal mechanism and Phase II/III trials demonstrate clinically meaningful symptom reduction with a distinct safety and interaction profile, offering an alternative for patients who cannot tolerate stimulants ...
Ghaith K. Mansour +4 more
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REVERSİBLE MAO İNHİBİTORS İN THE TREATMENT OF PANİC DISORDERS
Psychiatry and Clinical Psychopharmacology, 2021 Members of three classes of drugs have been shown to have efficacy-tricyclic antidepressants,monoamine oxidase inhibitors and benzodiazepins. Imipramine and clomipramine have been the tricyclic antidepressants most extensively studied.
Nesrin DİLBAZ +3 more
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Journal of Pharmacy & Pharmaceutical Sciences, 2008 PURPOSE. To compare phenelzine (PLZ), an antidepressant drug with anxiolytic properties which inhibits monoamine oxidase (MAO) but also elevates rat brain levels of the amino acids ?-aminobutyric acid (GABA) and alanine (ALA), with vigabatrin (VIG ...
Kathryn G. Todd, Glen B. Baker
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MedComm, Volume 7, Issue 3, March 2026.Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia +4 more
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