Results 31 to 40 of about 285,228 (311)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
C(sp3)–heteroatom bond formation by iron-catalyzed soft couplings
Communications ChemistryCarbon–heteroatom bonds are of great importance due to their prevalence in pharmaceuticals, agrochemicals, materials, and natural products. Despite the effective use of metal-catalyzed cross-coupling reactions between sp2-hybridized organohalides and ...
Julius Semenya +5 more
doaj +1 more source
ElectrochemistryA H15P3V6Mo18O84 aqueous solution containing phosphovanadomolybdate anions such as [PV3Mo9O40]6− and [PV2Mo10O40]5− were applied to a catholyte of redox flow polymer electrolyte fuel cells (PEFCs).
Shinji NARUSE +5 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Pharmaceuticals, 2021 Background: the proviral insertion site of Moloney murine leukemia (PIM) 1 kinase has served as a therapeutic target for various human cancers due to the enhancement of cell proliferation and the inhibition of apoptosis.
Hwangseo Park +4 more
doaj +1 more source
Effect of fertilizer formulation and bioaugmentation on biodegradation and leaching of crude oils and refined products in soils [PDF]
, 2012 The effects of soil characteristics and oil types as well as the efficacy of two fertilizer formulations and three bioaugmentation packages in improving the bioremediation of oil-contaminated soils were assessed as a means of ex situ treatment selection ...
Lethbridge, Gordon +8 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
HYDROCARBON MEASUREMENTS AND THEIR USE AS ATMOSPHERIC TRACERS [PDF]
, 2013 Non-methane hydrocarbons (NMHCs) have been measured in the boundary layer and free troposphere to investigate their behaviour under different atmospheric chemical regimes.
Punjabi, Shalini
core
Hydrocarbon Accumulation Model Controlled by Overpressure Evolution in the Kelasu Thrust Belt of the Kuqa Depression, NW China [PDF]
, 2022 The Kuqa Depression is the most representative overpressured hydrocarbon accumulation area in western China. The early rapid subsidence since 5 Ma and the strong uplift in the late period have led to a complicated evolution history of the overpressure ...
Nan Wu +4 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source