Results 131 to 140 of about 495,919 (291)

Impact of Nano‐Scale Defects on the Macroscopic Amplified Spontaneous Emission in Polycrystalline Perovskite Thin‐Films

Advanced Materials, EarlyView.
In this work, we discovered that optical gain within these polycrystalline perovskite thin films occurs primarily at defective sites, where, despite the low photoluminescence efficiency, we demonstrated high optical gain efficiency and long photocarrier lifetime. Our findings highlight the importance of defects in the development of electrically pumped
Chun‐Sheng Jack Wu, E Laine Wong, Hui Li, Jesús Jiménez‐López, Chia‐Kai Lin, Hsu‐Cheng Hsu, Annamaria Petrozza   +6 more
wiley   +1 more source

Bioinspired, Mitochondria‐Targeted Single‐Atom Nanozyme Enhances Bone Regeneration by Reprogramming Stem Cell Energy Metabolism​

Advanced Materials, EarlyView.
A bioinspired nanozyme—triphenylphosphonium (TPP)‐dendritic mesoporous silica nanoparticle (DMSN)‐Fe/Cu—mimics mitochondrial complex IV and targets mitochondria to regulate cellular energy metabolism. This approach markedly boosts bone regeneration in vivo, as demonstrated by enhanced bone volume and mineral density in critical‐sized bone defects rat ...
Yuwen Wang, Xinzhi Liang, Tiandi Xiong, Zheng Zhong, Ning Zhang, Boguang Yang, Dong Li, Qiongjiao Zeng, Xian Chen, Yiting Lei, Shangsi Chen, Chao Zheng, Liu Yang, Wei Huang, Rocky S. Tuan, Denghui Xie, Zhong Alan Li   +16 more
wiley   +1 more source

Data‐Driven Discovery of Quaternary Ammonium Interlayers for Efficient and Thermally Stable Perovskite Solar Cells

Advanced Materials, EarlyView.
An active learning framework, grounded in independently generated in‐house experimental data, enables reliable discovery of high‐performance interfacial materials for perovskite solar cells. Iterative model refinement autonomously converges toward structurally robust quaternary ammonium architectures, establishing a new design principle for interfacial
Jongbeom Kim, Yang Jeong Park, Chaehoon Jeon, Nahye Shin, Jaewang Park, Seungun Lee, Jino Im, Sungroh Yoon, Sang Il Seok   +8 more
wiley   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

Berberine hydrochloride inhibits the proliferation and metastasis of p53 mutant gallbladder Cancer cells by regulating the IL6/STAT3 pathway

Scientific Reports
Gallbladder cancer (GBC) is one of the most common biliary malignancies. Berberine hydrochloride, an compound extracted from the traditional Chinese medicinal plant Coptis chinensis, has potential therapeutic effects on various tumor cells. Therefore, we
Huan Zhang, Guoning Li, Lanxin Ni, Rui Wang, Lijun Peng, Lanlan Zang, Chunlei Lu, Zhi Wang, Jinghua Liu   +8 more
doaj   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Characterization of endonuclease activities in Moloney murine leukemia virus and its replication-defective mutants [PDF]

, 1987
To study Moloney murine leukemia virus (M-MulV) proteins associated with the integration of proviral DNA into the host chromosome, we isolated endonuclease activities from purified virion preparations of the wild type and two of its replication mutants ...
Baltimore, David, Panet, Amos
core  

Orientation Engineering of MXene Flakes

Advanced Materials, EarlyView.
Orientation engineering of MXene flakes refers to the transformation of disordered MXene flakes into ordered architectures with optimized multiphysical transport properties. Focusing on this topic, this review outlines key principles, characterization, fabrication strategies, and advanced applications of oriented MXene structures.
Yizhou Wang, Shuo Li, Tianchao Guo, Dekang Zhu, Ning Chu, Noor Albar, Dana Alsulaiman, Husam N. Alshareef   +7 more
wiley   +1 more source

Ractopamine HCl improved cardiac hypertrophy but not poor growth, metabolic inefficiency, or greater white blood cells associated with heat stress in concentrate-fed lambs [PDF]

, 2019
Heat stress decreases livestock performance and well-being (Hahn, 1999; Nienaber and Hahn, 2007), causes metabolic dysfunction that decreases growth efficiency (O’Brien et al., 2010), and alters cardiovascular function (Crandall et al., 2008). Each year,
Beede, Kristin A., Eggleston, Morgan L., Freeman, Micayla D., Petersen, Jessica L., Schmidt, Ty B., Swanson, Rebecca M., Yates, Dustin T.   +6 more
core   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

Advanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar, Carlos Alejandro Jimenez‐Rodriguez, Railia Biktimirova, Ilka Hermes, Thomas Kurth, My Duyen Pham, Mikhail Tsurkan, Jens Friedrichs, Francis L. C. Morgan, Hans Kleemann, Olga Guskova, Uwe Freudenberg, Peter Fratzl, Carsten Werner, Christoph Tondera, Ivan R. Minev   +15 more
wiley   +1 more source