Berberine hydrochloride enhances innate immunity to protect against pathogen infection via p38 MAPK pathway [PDF]
Frontiers in ImmunologyThe p38 MAPK pathway, an evolutionarily conserved mechanism, plays a crucial role in defending hosts against bacterial infections in both mammals and nematodes.
Yi Xiao +11 more
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Effects of berberine hydrochloride on immune response in the crab Charybdis japonica [PDF]
BMC Genomics, 2022 Berberine hydrochloride is the main effective component of Coptis spp. used in Chinese herbal medicine and its underlying molecular mechanisms, responsible for inducing effects in crustacean species, are not fully understood. In this study, the molecular
Tian-heng Gao +7 more
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Berberine hydrochloride combination therapy and efflux pump regulation mechanism ameliorates antimicrobial resistance of Acinetobacter baumannii [PDF]
Microbiology SpectrumAcinetobacter baumannii, a major pathogen that causes nosocomial infections, exhibits drug resistance. Efflux pumps are critical in developing multidrug resistance.
Jia Wang +8 more
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Berberine hydrochloride inhibits the proliferation and metastasis of p53 mutant gallbladder Cancer cells by regulating the IL6/STAT3 pathway [PDF]
Scientific ReportsGallbladder cancer (GBC) is one of the most common biliary malignancies. Berberine hydrochloride, an compound extracted from the traditional Chinese medicinal plant Coptis chinensis, has potential therapeutic effects on various tumor cells. Therefore, we
Huan Zhang +8 more
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Effects of berberine hydrochloride on antioxidant response and gut microflora in the Charybdis japonica infected with Aeromonas hydrophila [PDF]
BMC MicrobiologyThis study used berberine hydrochloride to treat the Asian paddle crab, Charybdis japonica infected with the Gram-negative bacterium Aeromonas hydrophila at concentrations of 0, 100, 200 and 300 mg/L. The effect of berberine hydrochloride on the survival
Mingming Han +10 more
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Neuroprotective Effects of Berberine Hydrochloride on Methamphetamine-induced Cognitive Dysfunction: Immunohistochemical and Behavioral Studies in Rats [PDF]
Basic and Clinical Neuroscience, 2022 Introduction: Methamphetamine (MA) as an addictive psychostimulant drug affects the central nervous system. The current research aimed to evaluate the impact of berberine hydrochloride on improving cognitive function and neuroprotective effects in rats ...
Leila Rezaeian +3 more
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The in vitro evaluation of synergistic effects of ciprofloxacin and berberine hydrochloride against Pseudomonas aeruginosa [PDF]
BMC MicrobiologyBackground Pseudomonas aeruginosa is a major cause of severe infections, leading to significant morbidity and mortality rates due to its ability of biofilm formation and antibiotic resistance.
Anis Zeraatpisheh +8 more
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Effects of berberine hydrochloride on methamphetamine-induced anxiety behaviors and relapse in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): This research aimed at evaluating the effect of berberine hydrochloride on anxiety-related behaviors induced by methamphetamine (METH) in rats, assessing relapse and neuroprotective effects.
Leila Rezaeian +4 more
doaj +2 more sources
Berberine hydrochloride alleviates chronic prostatitis/chronic pelvic pain syndrome by modifying gut microbiome signaling [PDF]
Asian Journal of AndrologyChronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is highly prevalent worldwide and poses a significant threat to men’s health, particularly affecting young men.
Yi-Qun Tian +7 more
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Inhibitory Effects of Berberine Hydrochloride on Trichophyton mentagrophytes and the Underlying Mechanisms [PDF]
Molecules, 2019 Background: T. mentagrophytes can infect all mammals, including rabbits, causing serious infections with remarkable economic losses for rabbit farmers.
Chen Wen Xiao +6 more
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