Results 241 to 250 of about 347,403 (310)

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou   +12 more
wiley   +1 more source

Priming Cells with Modulators of Cellular Signaling Ensures Enhanced Selectivity of HSPG-Specific Protein-Drug Conjugate Delivery. [PDF]

open access: yesJ Am Chem Soc
Chorążewska A   +13 more
europepmc   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

open access: yesAdvanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi   +8 more
wiley   +1 more source

Enhancement of intracellular saxitoxin accumulation by lidocaine HYDROCHLORIDE IN THE CYANOBACTERIUM CYLINDROSPERMOPSIS RACIBORSKII T3 (NOSTOCALES).

open access: yes, 2003
HYDROCHLORIDE IN THE CYANOBACTERIUM CYLINDROSPERMOPSIS RACIBORSKII T   +6 more
core  

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

open access: yesAdvanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou   +8 more
wiley   +1 more source

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