Results 271 to 280 of about 677,906 (386)

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Co-Amorphous Combination of Nateglinide-Metformin Hydrochloride for Dissolution Enhancement

AAPS PharmSciTech, 2015
Sarika Wairkar, R. Gaud
semanticscholar   +1 more source

Compounding and stability studies of liquid oral formulations of beta-blockers (bisoprolol, betaxolol, and nadolol) for paediatric patients. [PDF]

J Pharm Pharm Sci
Dubois L, Bouguergour C, Paoli-Lombardo R, Castera-Ducros C, Jean C, Fuchs M, Vanelle P, Rathelot P, Terme T, Curti C.   +9 more
europepmc   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Effect of Drotavarine Hydrochloride and A Combination of - Hyoscine–NButyl Bromide With Valethamate Bromide on the Duration of Active Phase of Labor - A Comparative Study

, 2017
Surbhi Saini
openalex   +1 more source

Effects of penehyclidine hydrochloride or droperidol combined with dexamethasone on preventing postoperative nausea and vomiting after remimazolam-alfentanil general anesthesia for gynecological day surgery. [PDF]

BMC Anesthesiol
Yu S, Shi X, Sun X, He F, Xiao H, Zhang R, Gu X, Ji F.   +7 more
europepmc   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Pharmacological studies on (2R)-(-)-2methyl-3-pyrrolidino-1-(4-trifluoromethylphenyl)propanone hydrochloride (NK433), a new centrally acting muscle relaxant(2): Effect on motor systems

, 1990
Yoshihito Ozawa, Katsuhiko Sakitama, Yoshiyuki Kojima, Naomi Aoto, Chikako Komai, M. Ishikawa   +5 more
openalex   +1 more source

RETRACTED: Ghose et al. Development and Evaluation of Polymeric Nanosponge Hydrogel for Terbinafine Hydrochloride: Statistical Optimization, In Vitro and In Vivo Studies. <i>Polymers</i> 2020, <i>12</i>, 2903. [PDF]

Polymers (Basel)
Ghose A, Nabi B, Rehman S, Md S, Alhakamy NA, Ahmad OAA, Baboota S, Ali J.   +7 more
europepmc   +1 more source

Participation of Deoxyribonucleic Acid Polymerase a in Amplification of Ribosomal Deoxyribonucleic Acid in Xenopus laevis [PDF]

, 1981
Zimmermann, Wolfgang
core