Results 41 to 50 of about 347,403 (310)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Novel N-phenyl-2-(aniline) benzamide hydrochloride salt development for colon cancer therapy
Frontiers in PharmacologyIntroductionN-phenyl-2-(aniline) analog N53 is a previously discovered dual inhibitor of Topo I and COX-2, which exhibited significant anti-colon cancer activity in vitro, but the poor solubility and moderate anti-cancer activity in vivo hindered its ...
Yan Peng +15 more
doaj +1 more source
Dental Research Journal, 2014 Background: Interaction between local anesthetic solution, lidocaine hydrochloride (with and without adrenaline), and root canal irrigants such as sodium hypochlorite (NaOCl), ethylene diamine tetra-acetic acid (EDTA), and chlorhexidine (CHX) has not ...
Nirmal Vidhya +4 more
doaj +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Acute Psychotic Symptoms due to Benzydamine Hydrochloride Abuse with Alcohol
Case Reports in Psychiatry, 2014 Benzydamine hydrochloride is a locally acting nonsteroidal anti-inflammatory drug. Benzydamine hydrochloride overdose can cause stimulation of central nervous system, hallucinations, and psychosis.
Yahya Ayhan Acar +4 more
doaj +1 more source
Advanced Functional Materials, EarlyView.DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen +3 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash +4 more
wiley +1 more source
COMPARATIVE LC-MS STABILITY INDICATIND ASSAYS OF ONDANSETRON HYDROCHLORIDE/NALOXONE HYDROCHLORIDE AND METOCLOPRAMIDE HYDROCHLORIDE/NALOXONE HYDROCHLORIDE USED IN PALLIATIVE CARE [PDF]
, 2015 Objectives: To compare the compatibility and chemical stability of ondansetron hydrochloride/naloxone hydrochloride and metoclopramide hydrochloride/naloxone hydrochloride admixtures used in palliative care units at three different storage conditions ...
Altannak, Naser F
core +1 more source
Nalfurafine hydrochloride to treat pruritus: a review [PDF]
, 2015 Shigeki InuiDepartment of Regenerative Dermatology, Osaka University Graduate School of Medicine, Osaka, JapanAbstract: Uremic pruritus has a great negative influence on quality of life in hemodialysis (HD) patients and, importantly, negatively affects ...
Inui S
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