Results 161 to 170 of about 123,936 (336)

Administration Studies in Equine Antidoping Research: Designing Scientific Investigations to Effectively Direct Medication Control in Racehorses

open access: yesDrug Testing and Analysis, EarlyView.
ABSTRACT Pharmacokinetics is the study of the movement of drug in the body and includes the processes of absorption, distribution, metabolism, and excretion. Pharmacodynamics is the pharmacologic effect of the drug on the body. The pharmacokinetics of a drug determines its pharmacologic effect. Pharmacokinetic studies describe drug concentrations while
Heather K. Knych
wiley   +1 more source

Computer‐aided Evaluation of Polyvalent Medications’ Pharmacological Potential. Multiphytoadaptogen as a Case Study

open access: yesMolecular Informatics, Volume 42, Issue 1, January 2023., 2023
Abstract Many human diseases including cancer, degenerative and autoimmune disorders, diabetes and others are multifactorial. Pharmaceutical agents acting on a single target do not provide their efficient curation. Multitargeted drugs exhibiting pleiotropic pharmacological effects have certain advantages due to the normalization of the complex ...
O. A. Bocharova   +18 more
wiley   +1 more source

Impact of Menstrual Cycle and Oral Contraceptives on Haematological and Inflammatory Biomarkers in Highly Trained Female Athletes

open access: yesDrug Testing and Analysis, EarlyView.
In highly trained female athletes, haematological and inflammatory biomarkers were found to be independent of menstrual cycle phase, but oral contraceptive use increased transferrin, reticulocyte count and triglycerides and decreased interleukin‐6.
Katia Collomp   +12 more
wiley   +1 more source

Biology and Management of Male‐Bodied Athletes in Elite Female Sports

open access: yesDrug Testing and Analysis, EarlyView.
Graphical representation of the relationships of transgender and XY DSDF as male‐bodied athletes along the binary dimensions of biological sex. ABSTRACT The physical advantages in elite power sports that allow men to surpass women are derived from the experience of male puberty.
David J. Handelsman, Stéphane Bermon
wiley   +1 more source

History of scurvy and use of vitamin C in critical illness: A narrative review

open access: yesNutrition in Clinical Practice, Volume 38, Issue 1, Page 46-54, February 2023., 2023
Abstract In 1747, an important milestone in the history of clinical research was set, as the Scottish surgeon James Lind conducted the first randomized controlled trial. Lind was interested in scurvy, a severe vitamin C deficiency which caused the death of thousands of British seamen.
Ellen Dresen   +5 more
wiley   +1 more source

Does immediate skin‐to‐skin contact at caesarean sections promote uterine contraction and recovery of the maternal blood haemoglobin levels? A randomized clinical trial

open access: yesNursing Open, Volume 10, Issue 2, Page 649-657, February 2023., 2023
Abstract Aim We analysed whether immediate skin‐to‐skin contact between the healthy newborn and the mother after a caesarean section has a modulatory role on postpartum haemorrhage and uterine contraction. Design Unblinded, randomized clinical trial, simple random sampling, conducted in women undergoing caesarean sections.
José Miguel Pérez‐Jiménez   +4 more
wiley   +1 more source

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