Results 191 to 200 of about 175,705 (335)
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li +12 more
wiley +1 more source
Predicting acute decompensated heart failure using circadian markers from heart rate time series
Circadian metrics—amplitude, mesor, and acrophase—derived from a wrist‐worn heart rate monitor can predict acute decompensated heart failure (ADHF) up to 21 days before onset. In 65 post‐ADHF patients, an LSTM model achieved 74% sensitivity, and 73% specificity trained on 21‐day sequences. These findings support circadian rhythm analysis as a promising
Valerie A. A. van Es +9 more
wiley +1 more source
Corticosteroids for sepsis and septic shock: a meta-analysis of 18 RCTs with dose-stratified and fludrocortisone subgroup evaluation. [PDF]
Ruyuan L +3 more
europepmc +1 more source
The effects of adrenalectomy and corticsteroid injection on the fibrinolytic activity of complex heparin compounds in the blood during immobilization [PDF]
Total non-enzymatic fibrinolytic activity in the blood of rats increased three times in response to stress caused by 30 minute immobilization, and the activity of epinephrine-heparin complex increased nine times. In adrenalectomized animals, which showed
Kudryashov, B. A. +3 more
core +1 more source
Aims Mineralocorticoid receptor antagonists (MRAs) are often underused in patients with heart failure (HF) and reduced ejection fraction (HFrEF). Individual treatment effect (ITE) may assist physicians in making timely decisions about which patients are the best suited for personalized therapy.
Masatake Kobayashi +9 more
wiley +1 more source
Hydrocortisone and Purinergic Signaling Stimulate Sodium/Iodide Symporter (NIS)-Mediated Iodide Transport in Breast Cancer Cells [PDF]
Orsolya Dohán +2 more
openalex +1 more source
Vicarious Touch: A Potential Substitute for Social Touch During Touch Deprivation
ABSTRACT Restricted interpersonal touch experiences, for instance due to COVID‐19 social distancing measures, result in detrimental effects on anxiety, loneliness and psychological well‐being. Yet, interventions capable of mitigating the impact of social touch deprivation, as experienced during the COVID‐19 pandemic, remain insufficient. In this study,
Louise P. Kirsch +3 more
wiley +1 more source
Development of a gene panel for immune status assessment in sepsis. [PDF]
Gao C +12 more
europepmc +1 more source

