Results 301 to 310 of about 132,529 (339)
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Journal of Pharmaceutical Sciences, 1972
Equations for use in studies of dissolution are derived from simple Noyes-Whitney kinetics. In one model the amount of drug added to the test system, Wo, is equal to the saturation capacity of the system, Ws In the second model an equation is derived for use when Wo ≠ Ws It was found that the dissolution of hydrocortisone, in both distilled water and ...
P. Sharkey, C.T. Rhodes, M.P. Short
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Equations for use in studies of dissolution are derived from simple Noyes-Whitney kinetics. In one model the amount of drug added to the test system, Wo, is equal to the saturation capacity of the system, Ws In the second model an equation is derived for use when Wo ≠ Ws It was found that the dissolution of hydrocortisone, in both distilled water and ...
P. Sharkey, C.T. Rhodes, M.P. Short
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Separation of hydrocortisone and epi-hydrocortisone by solvent extraction
Journal of Chemical Technology & Biotechnology, 1997Solvent extraction, instead of traditional crystallization, is suggested as a new method for separation of hydrocortisone and its optical isomer, epi-hydrocortisone. The extraction behavior of alcohols, ketones, esters, ethers and chlorinated hydrocarbons was studied experimentally.
Xien Hu, Tang Zhigang, Yongjun Zhu
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Hydrocortisone‐induced anaphylaxis
Medical Journal of Australia, 1984Two patients with asthma developed an anaphylactic reaction after the intravenous administration of hydrocortisone. In both cases, the reaction included the rapid development of airflow obstruction. Previous reports have suggested that the allergenic component may be hydrocortisone itself, rather than the diluents or preservatives.
Chan, CS +3 more
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Applied Microbiology and Biotechnology, 2013
Streptomyces roseochromogenes is able to hydroxylate steroid compounds in different positions of their cycloalkane rings thanks to a cytochrome P-450 multi-enzyme complex. In this paper, the hydroxylation of the hydrocortisone in the 16α position, performed by bacterial whole cells, was investigated in both shake flask and fermentation conditions; the ...
Odile Francesca Restaino +8 more
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Streptomyces roseochromogenes is able to hydroxylate steroid compounds in different positions of their cycloalkane rings thanks to a cytochrome P-450 multi-enzyme complex. In this paper, the hydroxylation of the hydrocortisone in the 16α position, performed by bacterial whole cells, was investigated in both shake flask and fermentation conditions; the ...
Odile Francesca Restaino +8 more
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Archives for Dermatological Research, 1976
In fresh human skin homogenates, the activities of four enzymes, lactate dehydrogenase (LDH), glucose-6-phosphate dehydrogenase (G-6-PDH), "acid" phosphatase (AcP), and "leucine aminopeptidase" (LAP) were assayed following an incubation with hydrocortisone, hydrocotisone acetate, or hydrocortisone-17-butyrate, respectively.
Bernard M. Gmeiner, Wolfgang P. Raab
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In fresh human skin homogenates, the activities of four enzymes, lactate dehydrogenase (LDH), glucose-6-phosphate dehydrogenase (G-6-PDH), "acid" phosphatase (AcP), and "leucine aminopeptidase" (LAP) were assayed following an incubation with hydrocortisone, hydrocotisone acetate, or hydrocortisone-17-butyrate, respectively.
Bernard M. Gmeiner, Wolfgang P. Raab
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Chlorocoulometric determination of hydrocortisone and hydrocortisone acetate.
Farmaco (Societa chimica italiana : 1989), 1991A chlorocoulometric method for the determination of small amounts of hydrocortisone and hydrocortisone acetate is presented. The method is simple and rapid, the results obtained are accurate and reproducible. It can be successfully applied to the determination of hydrocortisone and hydrocortisone acetate in pharmaceutical formulations.
Nikolić, Kosta +3 more
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2021
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis may worsen in septic shock, which is characterized by underlying circulatory, cellular, and metabolic abnormalities, associated with an increased risk of mortality [1].
Federico Longhini +2 more
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Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis may worsen in septic shock, which is characterized by underlying circulatory, cellular, and metabolic abnormalities, associated with an increased risk of mortality [1].
Federico Longhini +2 more
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2017
Hydrocortisone is a synthetic preparation of the steroid hormone cortisol. Hydrocortisone is usually absorbed very quickly from the gut with generally 95% of the dose absorbed. Cortisol measured in the blood following ingestion reaches a peak after 1–2 hours and lasts in the blood for approximately 6 hours. The half-life of cortisol (hydrocortisone) is
Peter C. Hindmarsh, Kathy Geertsma
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Hydrocortisone is a synthetic preparation of the steroid hormone cortisol. Hydrocortisone is usually absorbed very quickly from the gut with generally 95% of the dose absorbed. Cortisol measured in the blood following ingestion reaches a peak after 1–2 hours and lasts in the blood for approximately 6 hours. The half-life of cortisol (hydrocortisone) is
Peter C. Hindmarsh, Kathy Geertsma
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Anaphylaxis and Hydrocortisone
Annals of Internal Medicine, 1988Excerpt To the editor: We wish to report a case of anaphylaxis produced by intravenous administration of hydrocortisone sodium phosphate.
H al Mahdy, M Hall
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Determination of Hydrocortisone and Hydrocortisone Acetate in Antibiotic Mastitis Preparation
Journal of Pharmaceutical Sciences, 1966A modified column partition chromatographic method has been developed for the determination of hydrocortisone and hydrocortisone acetate in antibiotic mastitis preparations. A sodium bicarbonate trap under a methyl alcohol-water stationary phase in Celite is used with two mobile phases.
Alfred Bracey +2 more
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