Results 51 to 60 of about 126,784 (269)

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Design optimization of Bakelite support for LNG ISO tank 40 ft using finite element analysis

Curved and Layered Structures
Design optimization of a liquefied natural gas (LNG) ISO tank is essential to ensure structural integrity while minimizing weight. This approach enables the identification of efficient material distributions under critical loading conditions, enhancing ...
Tuswan Tuswan, Taufiq Rafif Naufal, Mursid Ocid, Sari Dian Purnama, Rizal Nandiko, Yuniati Yuniati, Sasmito Agus, Machfudin Andik, Sandjaja Irfan Eko, Utina Muhammad Ridwan, Harmadi Rudias, Muttaqie Teguh   +11 more
doaj   +1 more source

Vortex Characterization and Parametric Study of Miniature Vortex Generators and Their Near-Field Boundary Layer Effects

Applied Sciences
Delaying the onset of laminar-turbulent transition is an attractive method in reducing skin friction drag, especially on streamlined bodies where Tollmien–Schlichting instabilities are the dominating mechanism for transition. Miniature Vortex Generators (
Gilles De Baets, András Szabó, Péter Tamás Nagy, György Paál, Maarten Vanierschot   +4 more
doaj   +1 more source

Hazard assessment of a pair of glacial lakes in Nepal Himalaya: unfolding combined outbursts of Upper and Lower Barun

Geomatics, Natural Hazards & Risk, 2023
Due to climate change, the future Glacial Lake Outburst Flood (GLOF) risk is more likely in the Himalayas. Despite several GLOF studies, little attention has been given to the combined surge that can result from a pair of upstream-downstream glacial ...
Manish Raj Gouli, Kaiheng Hu, Nitesh Khadka, Rocky Talchabhadel   +3 more
doaj   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

Advanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett, Shahad K. Alsaiari, John L. Daristotle, Timothy A. Forster, Alicia Lau, Dhruv Varshney, Rania Afaneh, Andrew R. Hanna, Charles Sloane, David Mankus, Haitao Yu, Jiali Zhai, DongSoo Yun, Lisa H. Tostanoski, Abigail Lytton‐Jean, Dan H. Barouch, Charlotte E. Conn, Robert Langer, Ana Jaklenec, Calum J. Drummond   +19 more
wiley   +1 more source

Mechanisms of microparticle lateral manipulation using viscoelastic fluids in microchannels with triangle patterns array

Engineering Applications of Computational Fluid Mechanics
Microfluidic manipulation is widely used in lab-scale medical, chemical and environmental research. Passive methods of microparticle manipulation utilise only hydraulic forces in the fluid domain to enable size sorting, separation and purification of ...
Boran Zhang, Yue Fang, Jun Ma, Dan Yuan, Qihua Ran, Lin Liu, Mangmang Chen   +6 more
doaj   +1 more source

Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery

Advanced Functional Materials, EarlyView.
This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar, Deeksha Kumaresh, Eduardo Nombera Bueno, Mae Pryor, Paula T. Hammond   +4 more
wiley   +1 more source

Numerical Methodology for Determining the Energy Losses in Auxiliary Systems and Friction Processes Applied to Low Displacement Diesel Engines

Lubricants, 2020
The problem of climate change and the reduction of fossil fuels has motivated the development of research focused on improving the efficiency of internal combustion engines.
Sofia Orjuela Abril, Jhan Piero Rojas, Eder Norberto Flórez   +2 more
doaj   +1 more source

Hydrodynamic singularities [PDF]

, 2008
We give a brief overview of the physical significance of singularities in fluid mechanics.
openaire   +2 more sources

Advancements in Hypersaline Wastewater Treatment: The Promise of Quasi‐Liquid Surfaces to Reduce Salt Scaling

Advanced Functional Materials, EarlyView.
Durable quasi‐liquid polymer brush surfaces provide an anti‐scaling strategy for hypersaline brine evaporation and zero‐liquid‐discharge desalination. The smooth, liquid‐like QLS interface suppresses substrate‐side salt nucleation, promotes compact crystallization and dewetting, reduces crystal–surface contact area, and enables low‐adhesion salt ...
Mohammed Imran Khan, Bei Fan
wiley   +1 more source